Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

Lipids are closely associated with brain structure and function. However, the potential changes in the lipidome induced by aging remain to be elucidated. In this study, we used chromatographic techniques and a mass spectrometry-based approach to evaluate age-associated changes in the lipidome of the...

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Bibliographic Details
Main Authors:	Mariona Jové, Rosanna Cabré, Natàlia Mota-Martorell, Meritxell Martin-Garí, Èlia Obis, Paula Ramos, Iván Canales, José Daniel Galo-Licona, Joaquim Sol, Lara Nogueras, Pascual Torres, Manuel Portero-Otín, Victòria Ayala, Isidro Ferrer, Reinald Pamplona
Format:	article
Language:	EN
Published:	MDPI AG 2021
Subjects:	aging glycerolipids glycerophospholipids (lip)oxidation-derived protein damage markers mass spectrometry methionine restriction Biology (General) QH301-705.5 Chemistry QD1-999
Online Access:	https://doaj.org/article/7ee6724b919c4717b9a470ea865bed17
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Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

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