EFFICACY OF MAGNESIUM SULPHATE ON MATERNAL MORBIDITY AND MORTALITY IN ECLAMPSIA

Objective: To study efficacy of Magnesium Sulphate in reducing maternal morbidity and mortality in patients presenting with eclampsia. Study Design: Prospective observational study. Place and Duration of Study: Gynae/Obs Department, Combined Military Hospital Bannu, from Jan 2018 Sep 2019....

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Autores principales: Nadia Arif, Raja Qaseem Ahmed, Bushra Zafar, Farrukh Shehzad
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Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2021
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spelling oai:doaj.org-article:7ee96aba507f427baa725d143614757e2021-12-02T18:01:40ZEFFICACY OF MAGNESIUM SULPHATE ON MATERNAL MORBIDITY AND MORTALITY IN ECLAMPSIA0030-96482411-884210.51253/pafmj.v71i2.4100https://doaj.org/article/7ee96aba507f427baa725d143614757e2021-04-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/4100https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To study efficacy of Magnesium Sulphate in reducing maternal morbidity and mortality in patients presenting with eclampsia. Study Design: Prospective observational study. Place and Duration of Study: Gynae/Obs Department, Combined Military Hospital Bannu, from Jan 2018 Sep 2019. Methodology: A total of 134 patients fulfilling inclusion criteria were included in the study. Patient management was multidisciplinary. Convulsions were controlled by 4gram magnesium sulphate intravenously over 20 minutes as a loading dose, followed by 1gram per hour of maintenance infusion. Blood pressure was controlled with injection Labetalol 10 milligram followed by injection Hydralazine repeated after every 20 minutes till the blood pressure was controlled. Results: A total of 134 patients had eclampsia constituting 6.8% of obstetric admissions. Case fatality was 14 (10.4%) while 120 (89.55%) of the cases responded well to treatment and survived the event. Mean age of patients was 22 years. Thirty patients 22.4% were booked and 104 patients 77.6% were un-booked. Mostly patients 122 (91%) came from rural area and only 12 (9%) were from urban areas with booked pregnancies having regular antenatal visits. One hundred and twenty six (94%) patients with eclampsia presented in antenatal period and only 8 (6%) presented in post natal period. Mode of delivery was cesarean section in 87 (64.9%) and 47 (35.1%) delivered vaginally. Frequency of patient requiring ventilator support, acute renal failure, disseminated intravascular coagulation, adult respiratory distress syndrome, HELLP (hemolysis, elevated liver enzymes, low platelet) syndrome was 11 (8.2%), 46 (34.3%), 43 (32.1%), 35 (26.1%), 7 (5.2%) respectively..........Nadia ArifRaja Qaseem AhmedBushra ZafarFarrukh ShehzadArmy Medical College Rawalpindiarticleeclampsiamagnesium sulphatematernal morbiditymaternal mortalitypulmonary edemaMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 2, Pp 598-601 (2021)
institution DOAJ
collection DOAJ
language EN
topic eclampsia
magnesium sulphate
maternal morbidity
maternal mortality
pulmonary edema
Medicine
R
Medicine (General)
R5-920
spellingShingle eclampsia
magnesium sulphate
maternal morbidity
maternal mortality
pulmonary edema
Medicine
R
Medicine (General)
R5-920
Nadia Arif
Raja Qaseem Ahmed
Bushra Zafar
Farrukh Shehzad
EFFICACY OF MAGNESIUM SULPHATE ON MATERNAL MORBIDITY AND MORTALITY IN ECLAMPSIA
description Objective: To study efficacy of Magnesium Sulphate in reducing maternal morbidity and mortality in patients presenting with eclampsia. Study Design: Prospective observational study. Place and Duration of Study: Gynae/Obs Department, Combined Military Hospital Bannu, from Jan 2018 Sep 2019. Methodology: A total of 134 patients fulfilling inclusion criteria were included in the study. Patient management was multidisciplinary. Convulsions were controlled by 4gram magnesium sulphate intravenously over 20 minutes as a loading dose, followed by 1gram per hour of maintenance infusion. Blood pressure was controlled with injection Labetalol 10 milligram followed by injection Hydralazine repeated after every 20 minutes till the blood pressure was controlled. Results: A total of 134 patients had eclampsia constituting 6.8% of obstetric admissions. Case fatality was 14 (10.4%) while 120 (89.55%) of the cases responded well to treatment and survived the event. Mean age of patients was 22 years. Thirty patients 22.4% were booked and 104 patients 77.6% were un-booked. Mostly patients 122 (91%) came from rural area and only 12 (9%) were from urban areas with booked pregnancies having regular antenatal visits. One hundred and twenty six (94%) patients with eclampsia presented in antenatal period and only 8 (6%) presented in post natal period. Mode of delivery was cesarean section in 87 (64.9%) and 47 (35.1%) delivered vaginally. Frequency of patient requiring ventilator support, acute renal failure, disseminated intravascular coagulation, adult respiratory distress syndrome, HELLP (hemolysis, elevated liver enzymes, low platelet) syndrome was 11 (8.2%), 46 (34.3%), 43 (32.1%), 35 (26.1%), 7 (5.2%) respectively..........
format article
author Nadia Arif
Raja Qaseem Ahmed
Bushra Zafar
Farrukh Shehzad
author_facet Nadia Arif
Raja Qaseem Ahmed
Bushra Zafar
Farrukh Shehzad
author_sort Nadia Arif
title EFFICACY OF MAGNESIUM SULPHATE ON MATERNAL MORBIDITY AND MORTALITY IN ECLAMPSIA
title_short EFFICACY OF MAGNESIUM SULPHATE ON MATERNAL MORBIDITY AND MORTALITY IN ECLAMPSIA
title_full EFFICACY OF MAGNESIUM SULPHATE ON MATERNAL MORBIDITY AND MORTALITY IN ECLAMPSIA
title_fullStr EFFICACY OF MAGNESIUM SULPHATE ON MATERNAL MORBIDITY AND MORTALITY IN ECLAMPSIA
title_full_unstemmed EFFICACY OF MAGNESIUM SULPHATE ON MATERNAL MORBIDITY AND MORTALITY IN ECLAMPSIA
title_sort efficacy of magnesium sulphate on maternal morbidity and mortality in eclampsia
publisher Army Medical College Rawalpindi
publishDate 2021
url https://doaj.org/article/7ee96aba507f427baa725d143614757e
work_keys_str_mv AT nadiaarif efficacyofmagnesiumsulphateonmaternalmorbidityandmortalityineclampsia
AT rajaqaseemahmed efficacyofmagnesiumsulphateonmaternalmorbidityandmortalityineclampsia
AT bushrazafar efficacyofmagnesiumsulphateonmaternalmorbidityandmortalityineclampsia
AT farrukhshehzad efficacyofmagnesiumsulphateonmaternalmorbidityandmortalityineclampsia
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