NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity

Calcitonin receptor-expressing neurons of the nucleus tractus solitarius contribute to long-term control of food intake and body weight. The authors show that a subset of these cells expresses Prlh and that enhancing Prlh-mediated neurotransmission from the NTS dampens hypothalamically-driven hyperp...

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Autores principales:	Wenwen Cheng, Ermelinda Ndoka, Jessica N. Maung, Warren Pan, Alan C. Rupp, Christopher J. Rhodes, David P. Olson, Martin G. Myers
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7ee988d06c344cb69da88198bf19969f
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spelling	oai:doaj.org-article:7ee988d06c344cb69da88198bf19969f2021-12-02T15:25:36ZNTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity10.1038/s41467-021-25525-32041-1723https://doaj.org/article/7ee988d06c344cb69da88198bf19969f2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25525-3https://doaj.org/toc/2041-1723Calcitonin receptor-expressing neurons of the nucleus tractus solitarius contribute to long-term control of food intake and body weight. The authors show that a subset of these cells expresses Prlh and that enhancing Prlh-mediated neurotransmission from the NTS dampens hypothalamically-driven hyperphagia and obesity in mice.Wenwen ChengErmelinda NdokaJessica N. MaungWarren PanAlan C. RuppChristopher J. RhodesDavid P. OlsonMartin G. MyersNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wenwen Cheng Ermelinda Ndoka Jessica N. Maung Warren Pan Alan C. Rupp Christopher J. Rhodes David P. Olson Martin G. Myers NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity
description	Calcitonin receptor-expressing neurons of the nucleus tractus solitarius contribute to long-term control of food intake and body weight. The authors show that a subset of these cells expresses Prlh and that enhancing Prlh-mediated neurotransmission from the NTS dampens hypothalamically-driven hyperphagia and obesity in mice.
format	article
author	Wenwen Cheng Ermelinda Ndoka Jessica N. Maung Warren Pan Alan C. Rupp Christopher J. Rhodes David P. Olson Martin G. Myers
author_facet	Wenwen Cheng Ermelinda Ndoka Jessica N. Maung Warren Pan Alan C. Rupp Christopher J. Rhodes David P. Olson Martin G. Myers
author_sort	Wenwen Cheng
title	NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity
title_short	NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity
title_full	NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity
title_fullStr	NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity
title_full_unstemmed	NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity
title_sort	nts prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7ee988d06c344cb69da88198bf19969f
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NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity

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