Chemical labelling for visualizing native AMPA receptors in live neurons

Visualizing neurotransmitter receptor traffic is fundamental to understanding brain functions, but the current imaging methods can compromise the process. Here, the authors synthesize small fluorescent probes to label endogenous glutamate receptors in cell cultures and brain tissues, without affecti...

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Autores principales: Sho Wakayama, Shigeki Kiyonaka, Itaru Arai, Wataru Kakegawa, Shinji Matsuda, Keiji Ibata, Yuri L. Nemoto, Akihiro Kusumi, Michisuke Yuzaki, Itaru Hamachi
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7eea3380bd2546d2924bb2c3f664fc62
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spelling oai:doaj.org-article:7eea3380bd2546d2924bb2c3f664fc622021-12-02T14:42:42ZChemical labelling for visualizing native AMPA receptors in live neurons10.1038/ncomms148502041-1723https://doaj.org/article/7eea3380bd2546d2924bb2c3f664fc622017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14850https://doaj.org/toc/2041-1723Visualizing neurotransmitter receptor traffic is fundamental to understanding brain functions, but the current imaging methods can compromise the process. Here, the authors synthesize small fluorescent probes to label endogenous glutamate receptors in cell cultures and brain tissues, without affecting their function.Sho WakayamaShigeki KiyonakaItaru AraiWataru KakegawaShinji MatsudaKeiji IbataYuri L. NemotoAkihiro KusumiMichisuke YuzakiItaru HamachiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sho Wakayama
Shigeki Kiyonaka
Itaru Arai
Wataru Kakegawa
Shinji Matsuda
Keiji Ibata
Yuri L. Nemoto
Akihiro Kusumi
Michisuke Yuzaki
Itaru Hamachi
Chemical labelling for visualizing native AMPA receptors in live neurons
description Visualizing neurotransmitter receptor traffic is fundamental to understanding brain functions, but the current imaging methods can compromise the process. Here, the authors synthesize small fluorescent probes to label endogenous glutamate receptors in cell cultures and brain tissues, without affecting their function.
format article
author Sho Wakayama
Shigeki Kiyonaka
Itaru Arai
Wataru Kakegawa
Shinji Matsuda
Keiji Ibata
Yuri L. Nemoto
Akihiro Kusumi
Michisuke Yuzaki
Itaru Hamachi
author_facet Sho Wakayama
Shigeki Kiyonaka
Itaru Arai
Wataru Kakegawa
Shinji Matsuda
Keiji Ibata
Yuri L. Nemoto
Akihiro Kusumi
Michisuke Yuzaki
Itaru Hamachi
author_sort Sho Wakayama
title Chemical labelling for visualizing native AMPA receptors in live neurons
title_short Chemical labelling for visualizing native AMPA receptors in live neurons
title_full Chemical labelling for visualizing native AMPA receptors in live neurons
title_fullStr Chemical labelling for visualizing native AMPA receptors in live neurons
title_full_unstemmed Chemical labelling for visualizing native AMPA receptors in live neurons
title_sort chemical labelling for visualizing native ampa receptors in live neurons
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/7eea3380bd2546d2924bb2c3f664fc62
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