Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche
Acetylcholine regulates intestinal epithelial secretion via muscarinic Gq-coupled receptors but its role in cell differentiation is unclear. Here, the authors show that Prox1-positive endocrine cells are sensors for the cholinergic intestinal niche and can trigger increased differentiation of entero...
Guardado en:
Autores principales: | Moritz Middelhoff, Henrik Nienhüser, Giovanni Valenti, H. Carlo Maurer, Yoku Hayakawa, Ryota Takahashi, Woosook Kim, Zhengyu Jiang, Ermanno Malagola, Krystle Cuti, Yagnesh Tailor, Leah B. Zamechek, Bernhard W. Renz, Michael Quante, Kelley S. Yan, Timothy C. Wang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7eeb82d636ca4537aa0b570f2e30840f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
prox1b Activity is essential in zebrafish lymphangiogenesis.
por: Luca Del Giacco, et al.
Publicado: (2010) -
PROX1 is a transcriptional regulator of MMP14
por: Silvia Gramolelli, et al.
Publicado: (2018) -
Prox1 regulates the notch1-mediated inhibition of neurogenesis.
por: Valeria Kaltezioti, et al.
Publicado: (2010) -
The association of transcription factor Prox1 with the proliferation, migration, and invasion of lung cancer
por: Hao Xinxin, et al.
Publicado: (2021) -
Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis.
por: Alfonso Lavado, et al.
Publicado: (2010)