NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death
Several studies have revealed a correlation between chronic inflammation and nicotinamide adenine dinucleotide (NAD+) metabolism, but the precise mechanism involved is unknown. Here, we report that the genetic and pharmacological inhibition of nicotinamide phosphoribosyltransferase (Nampt), the rate...
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| Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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| Acceso en línea: | https://doaj.org/article/7eee5ee7fb2a4382a2dfaadd0d7636f1 |
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por Francisco J Martínez-Morcillo, Joaquín Cantón-Sandoval, Francisco J Martínez-Navarro, Isabel Cabas, Idoya Martínez-Vicente, Joy Armistead, Julia Hatzold, Azucena López-Muñoz, Teresa Martínez-Menchón, Raúl Corbalán-Vélez, Jesús Lacal, Matthias Hammerschmidt, José C García-Borrón, Alfonsa García-Ayala, María L Cayuela, Ana B Pérez-Oliva, Diana García-Moreno, Victoriano Mulero
Publicado 2021
Enlace del recursoPublicado 2021
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