IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice

Abstract Recent research has shown that reparative (alternatively activated or M2) macrophages play a role in repair of damaged tissues, including the infarcted hearts. Administration of IL-4 is known to augment M2 macrophages. This translational study thus aimed to investigate whether IL-4 administ...

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Autores principales: Yusuke Shintani, Tomoya Ito, Laura Fields, Manabu Shiraishi, Yuki Ichihara, Nobuhiko Sato, Mihai Podaru, Satoshi Kainuma, Hiroyuki Tanaka, Ken Suzuki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/7eff01afd9364ae088d1c82536260763
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