Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

Treatment response in patient-derived models may serve as a biomarker for response in the clinic. Here, the authors use paired patient-derived mouse xenografts and patient-derived primary culture models from head and neck squamous cell carcinomas, including metastasis, as models for high-throughput...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Shumei Chia, Joo-Leng Low, Xiaoqian Zhang, Xue-Lin Kwang, Fui-Teen Chong, Ankur Sharma, Denis Bertrand, Shen Yon Toh, Hui-Sun Leong, Matan T. Thangavelu, Jacqueline S. G. Hwang, Kok-Hing Lim, Thakshayeni Skanthakumar, Hiang-Khoon Tan, Yan Su, Siang Hui Choo, Hannes Hentze, Iain B. H. Tan, Alexander Lezhava, Patrick Tan, Daniel S. W. Tan, Giridharan Periyasamy, Judice L. Y. Koh, N. Gopalakrishna Iyer, Ramanuj DasGupta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/7f061de7c66f4a4eb132f00dff006462
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Treatment response in patient-derived models may serve as a biomarker for response in the clinic. Here, the authors use paired patient-derived mouse xenografts and patient-derived primary culture models from head and neck squamous cell carcinomas, including metastasis, as models for high-throughput screening of anti-cancer drugs.

Ejemplares similares