Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless
Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances the diffusion of the cell signalling protein Wingl...
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Nature Portfolio
2021
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oai:doaj.org-article:7f17f13f747943899fbf04ba7e53500e2021-12-02T17:37:36ZPegasus, a small extracellular peptide enhancing short-range diffusion of Wingless10.1038/s41467-021-25785-z2041-1723https://doaj.org/article/7f17f13f747943899fbf04ba7e53500e2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25785-zhttps://doaj.org/toc/2041-1723Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances the diffusion of the cell signalling protein Wingless.Emile G. MagnyAna Isabel PlateroSarah A. BishopJose I. PueyoDaniel Aguilar-HidalgoJuan Pablo CousoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
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Science Q Emile G. Magny Ana Isabel Platero Sarah A. Bishop Jose I. Pueyo Daniel Aguilar-Hidalgo Juan Pablo Couso Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless |
description |
Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances the diffusion of the cell signalling protein Wingless. |
format |
article |
author |
Emile G. Magny Ana Isabel Platero Sarah A. Bishop Jose I. Pueyo Daniel Aguilar-Hidalgo Juan Pablo Couso |
author_facet |
Emile G. Magny Ana Isabel Platero Sarah A. Bishop Jose I. Pueyo Daniel Aguilar-Hidalgo Juan Pablo Couso |
author_sort |
Emile G. Magny |
title |
Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless |
title_short |
Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless |
title_full |
Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless |
title_fullStr |
Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless |
title_full_unstemmed |
Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless |
title_sort |
pegasus, a small extracellular peptide enhancing short-range diffusion of wingless |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/7f17f13f747943899fbf04ba7e53500e |
work_keys_str_mv |
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