Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless

Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances the diffusion of the cell signalling protein Wingl...

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Autores principales: Emile G. Magny, Ana Isabel Platero, Sarah A. Bishop, Jose I. Pueyo, Daniel Aguilar-Hidalgo, Juan Pablo Couso
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7f17f13f747943899fbf04ba7e53500e
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spelling oai:doaj.org-article:7f17f13f747943899fbf04ba7e53500e2021-12-02T17:37:36ZPegasus, a small extracellular peptide enhancing short-range diffusion of Wingless10.1038/s41467-021-25785-z2041-1723https://doaj.org/article/7f17f13f747943899fbf04ba7e53500e2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25785-zhttps://doaj.org/toc/2041-1723Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances the diffusion of the cell signalling protein Wingless.Emile G. MagnyAna Isabel PlateroSarah A. BishopJose I. PueyoDaniel Aguilar-HidalgoJuan Pablo CousoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Emile G. Magny
Ana Isabel Platero
Sarah A. Bishop
Jose I. Pueyo
Daniel Aguilar-Hidalgo
Juan Pablo Couso
Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless
description Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances the diffusion of the cell signalling protein Wingless.
format article
author Emile G. Magny
Ana Isabel Platero
Sarah A. Bishop
Jose I. Pueyo
Daniel Aguilar-Hidalgo
Juan Pablo Couso
author_facet Emile G. Magny
Ana Isabel Platero
Sarah A. Bishop
Jose I. Pueyo
Daniel Aguilar-Hidalgo
Juan Pablo Couso
author_sort Emile G. Magny
title Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless
title_short Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless
title_full Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless
title_fullStr Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless
title_full_unstemmed Pegasus, a small extracellular peptide enhancing short-range diffusion of Wingless
title_sort pegasus, a small extracellular peptide enhancing short-range diffusion of wingless
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7f17f13f747943899fbf04ba7e53500e
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