ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)

Abstract. We analyzed efficiency of application for analytic control parameters, i.e., «T-cell replicates» and «T-cell summary» in a sample of 174 HIV-infected patients, independently of age or disease stage. The patients were divided in two groups. Group 1 consisted of patients with total CD45+CD3+...

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Autores principales:	E. V. Shestakova, A. V. Zurochka, S. V. Kviatkovskaya, S. G. Betskov, V. V. Dukardt, S. V. Haidukov
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	flow cytometry t-lymphocytes hiv Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/7f32b4c96c114105a23c26bdc319fe09
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spelling	oai:doaj.org-article:7f32b4c96c114105a23c26bdc319fe092021-11-18T08:03:39ZANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)1563-06252313-741X10.15789/1563-0625-2008-4-5-463-466https://doaj.org/article/7f32b4c96c114105a23c26bdc319fe092014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/219https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We analyzed efficiency of application for analytic control parameters, i.e., «T-cell replicates» and «T-cell summary» in a sample of 174 HIV-infected patients, independently of age or disease stage. The patients were divided in two groups. Group 1 consisted of patients with total CD45+CD3+CD4+ and CD45+CD3+CD8+ lymphocyte concentrations being similar to relative and absolute concentrations of CD45+CD3+ lymphocytes, or the difference between absolute measurements not exceeding «T-cell replicates» differences. Group 1 included 36.78% of the whole cohort. Group 2 consisted of patients with total CD45+CD3+CD4+ & CD45+CD3+CD8+ lymphocytes concentrations being lower than relative and absolute concentrations of CD45+CD3+ lymphocytes, and the differences in absolute values being higher than «T-cell replicates» differences (41.38% of total sample). Such difference between control sums may be connected with high concentrations of double-negative γδ-T-cells (CD45+CD3+CD4–CD8–) in the specimens under study. (Med. Immunol., 2008, vol. 10, N 4-5, pp 463-466).E. V. ShestakovaA. V. ZurochkaS. V. KviatkovskayaS. G. BetskovV. V. DukardtS. V. HaidukovSPb RAACIarticleflow cytometryt-lymphocyteshivImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 10, Iss 4-5, Pp 463-466 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	flow cytometry t-lymphocytes hiv Immunologic diseases. Allergy RC581-607
spellingShingle	flow cytometry t-lymphocytes hiv Immunologic diseases. Allergy RC581-607 E. V. Shestakova A. V. Zurochka S. V. Kviatkovskaya S. G. Betskov V. V. Dukardt S. V. Haidukov ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)
description	Abstract. We analyzed efficiency of application for analytic control parameters, i.e., «T-cell replicates» and «T-cell summary» in a sample of 174 HIV-infected patients, independently of age or disease stage. The patients were divided in two groups. Group 1 consisted of patients with total CD45+CD3+CD4+ and CD45+CD3+CD8+ lymphocyte concentrations being similar to relative and absolute concentrations of CD45+CD3+ lymphocytes, or the difference between absolute measurements not exceeding «T-cell replicates» differences. Group 1 included 36.78% of the whole cohort. Group 2 consisted of patients with total CD45+CD3+CD4+ & CD45+CD3+CD8+ lymphocytes concentrations being lower than relative and absolute concentrations of CD45+CD3+ lymphocytes, and the differences in absolute values being higher than «T-cell replicates» differences (41.38% of total sample). Such difference between control sums may be connected with high concentrations of double-negative γδ-T-cells (CD45+CD3+CD4–CD8–) in the specimens under study. (Med. Immunol., 2008, vol. 10, N 4-5, pp 463-466).
format	article
author	E. V. Shestakova A. V. Zurochka S. V. Kviatkovskaya S. G. Betskov V. V. Dukardt S. V. Haidukov
author_facet	E. V. Shestakova A. V. Zurochka S. V. Kviatkovskaya S. G. Betskov V. V. Dukardt S. V. Haidukov
author_sort	E. V. Shestakova
title	ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)
title_short	ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)
title_full	ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)
title_fullStr	ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)
title_full_unstemmed	ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)
title_sort	analysis of control measurements of «t-cell replicates» and «t-cell summary» in investigation of the immune status of hiv-infected patients and detection double negative subpopulation of t-lymphocytes (cd45+cd3+cd4–cd8–)
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/7f32b4c96c114105a23c26bdc319fe09
work_keys_str_mv	AT evshestakova analysisofcontrolmeasurementsoftcellreplicatesandtcellsummaryininvestigationoftheimmunestatusofhivinfectedpatientsanddetectiondoublenegativesubpopulationoftlymphocytescd45cd3cd4cd8 AT avzurochka analysisofcontrolmeasurementsoftcellreplicatesandtcellsummaryininvestigationoftheimmunestatusofhivinfectedpatientsanddetectiondoublenegativesubpopulationoftlymphocytescd45cd3cd4cd8 AT svkviatkovskaya analysisofcontrolmeasurementsoftcellreplicatesandtcellsummaryininvestigationoftheimmunestatusofhivinfectedpatientsanddetectiondoublenegativesubpopulationoftlymphocytescd45cd3cd4cd8 AT sgbetskov analysisofcontrolmeasurementsoftcellreplicatesandtcellsummaryininvestigationoftheimmunestatusofhivinfectedpatientsanddetectiondoublenegativesubpopulationoftlymphocytescd45cd3cd4cd8 AT vvdukardt analysisofcontrolmeasurementsoftcellreplicatesandtcellsummaryininvestigationoftheimmunestatusofhivinfectedpatientsanddetectiondoublenegativesubpopulationoftlymphocytescd45cd3cd4cd8 AT svhaidukov analysisofcontrolmeasurementsoftcellreplicatesandtcellsummaryininvestigationoftheimmunestatusofhivinfectedpatientsanddetectiondoublenegativesubpopulationoftlymphocytescd45cd3cd4cd8
_version_	1718422554223312896

ANALYSIS OF CONTROL MEASUREMENTS OF «T-CELL REPLICATES» AND «T-CELL SUMMARY» IN INVESTIGATION OF THE IMMUNE STATUS OF HIV-INFECTED PATIENTS AND DETECTION DOUBLE NEGATIVE SUBPOPULATION OF T-LYMPHOCYTES (CD45+CD3+CD4–CD8–)

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