Research Progress on Quality Control Methods for Xiaochaihu Preparations

Xiaochaihu (XCH) is a classic Chinese medicine formula. XCH tablet, XCH granule, XCH capsule, and XCH effervescent tablet are included in the Chinese Pharmacopoeia. In this review, the formula and quality standards of XCH preparations at home and abroad were compared. The differences in manufacturin...

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Autores principales:	Guangzheng Xu, Hui Wang, Yingqian Deng, Keyi Xie, Weibo Zhao, Xingchu Gong
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	Xiaochaihu (XCH) formula preparations quality control standard Physics QC1-999 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/7f3c76fe29594ca1937d66f29ae2980b
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spelling	oai:doaj.org-article:7f3c76fe29594ca1937d66f29ae2980b2021-11-25T18:59:18ZResearch Progress on Quality Control Methods for Xiaochaihu Preparations10.3390/separations81101992297-8739https://doaj.org/article/7f3c76fe29594ca1937d66f29ae2980b2021-11-01T00:00:00Zhttps://www.mdpi.com/2297-8739/8/11/199https://doaj.org/toc/2297-8739Xiaochaihu (XCH) is a classic Chinese medicine formula. XCH tablet, XCH granule, XCH capsule, and XCH effervescent tablet are included in the Chinese Pharmacopoeia. In this review, the formula and quality standards of XCH preparations at home and abroad were compared. The differences in manufacturing process of XCH preparations are discussed. The progress of research on the qualitative identification, quantitative detection and fingerprint chromatogram/specific chromatogram of XCH preparations was reviewed. The characteristic components of Pinelliae Rhizoma Praeparatum Cum Zingibere Et Alumine and Jujubae Fructus was rarely analyzed for XCH preparations. It is suggested that the specificity of drug quality detection methods should be improved. Considering drug safety and drug efficacy, it is suggested to set the upper and lower limits of the content of saikosaponins. The standards for heavy metals and other limited items for XCH preparations are also suggested to be set.Guangzheng XuHui WangYingqian DengKeyi XieWeibo ZhaoXingchu GongMDPI AGarticleXiaochaihu (XCH) formulapreparationsquality controlstandardPhysicsQC1-999ChemistryQD1-999ENSeparations, Vol 8, Iss 199, p 199 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Xiaochaihu (XCH) formula preparations quality control standard Physics QC1-999 Chemistry QD1-999
spellingShingle	Xiaochaihu (XCH) formula preparations quality control standard Physics QC1-999 Chemistry QD1-999 Guangzheng Xu Hui Wang Yingqian Deng Keyi Xie Weibo Zhao Xingchu Gong Research Progress on Quality Control Methods for Xiaochaihu Preparations
description	Xiaochaihu (XCH) is a classic Chinese medicine formula. XCH tablet, XCH granule, XCH capsule, and XCH effervescent tablet are included in the Chinese Pharmacopoeia. In this review, the formula and quality standards of XCH preparations at home and abroad were compared. The differences in manufacturing process of XCH preparations are discussed. The progress of research on the qualitative identification, quantitative detection and fingerprint chromatogram/specific chromatogram of XCH preparations was reviewed. The characteristic components of Pinelliae Rhizoma Praeparatum Cum Zingibere Et Alumine and Jujubae Fructus was rarely analyzed for XCH preparations. It is suggested that the specificity of drug quality detection methods should be improved. Considering drug safety and drug efficacy, it is suggested to set the upper and lower limits of the content of saikosaponins. The standards for heavy metals and other limited items for XCH preparations are also suggested to be set.
format	article
author	Guangzheng Xu Hui Wang Yingqian Deng Keyi Xie Weibo Zhao Xingchu Gong
author_facet	Guangzheng Xu Hui Wang Yingqian Deng Keyi Xie Weibo Zhao Xingchu Gong
author_sort	Guangzheng Xu
title	Research Progress on Quality Control Methods for Xiaochaihu Preparations
title_short	Research Progress on Quality Control Methods for Xiaochaihu Preparations
title_full	Research Progress on Quality Control Methods for Xiaochaihu Preparations
title_fullStr	Research Progress on Quality Control Methods for Xiaochaihu Preparations
title_full_unstemmed	Research Progress on Quality Control Methods for Xiaochaihu Preparations
title_sort	research progress on quality control methods for xiaochaihu preparations
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/7f3c76fe29594ca1937d66f29ae2980b
work_keys_str_mv	AT guangzhengxu researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT huiwang researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT yingqiandeng researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT keyixie researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT weibozhao researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT xingchugong researchprogressonqualitycontrolmethodsforxiaochaihupreparations
_version_	1718410472138473472

Research Progress on Quality Control Methods for Xiaochaihu Preparations

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