Injection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.

<h4>Purpose</h4>Experimental study to measure the intraocular lens (IOL) injection time and injection speed at different intraocular pressure (IOP) settings when using the AutonoMe® injector.<h4>Methods</h4>In this experimental study, following phacoemulsification in porcine...

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Autores principales: Jan N Weindler, Tadas Naujokaitis, Sonja K Schickhardt, Ramin Khoramnia, Gerd U Auffarth
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Publicado: Public Library of Science (PLoS) 2021
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spelling oai:doaj.org-article:7f3d1ca565da40aa91059e8c07323a1e2021-12-02T20:06:48ZInjection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.1932-620310.1371/journal.pone.0254901https://doaj.org/article/7f3d1ca565da40aa91059e8c07323a1e2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0254901https://doaj.org/toc/1932-6203<h4>Purpose</h4>Experimental study to measure the intraocular lens (IOL) injection time and injection speed at different intraocular pressure (IOP) settings when using the AutonoMe® injector.<h4>Methods</h4>In this experimental study, following phacoemulsification in porcine cadaver eyes, a trocar was inserted at pars plana with a connected infusion and IOPs of 20, 50 and 80 mmHg were generated by altering the infusion height. Twelve CO2 gas-driven injectors were used to implant an IOL via a corneal incision of 2.2 mm. For each IOP setting, the duration of the IOL injection and the injection speed was measured by analyzing a video recording of the procedure.<h4>Results</h4>The mean ±SD injection time (seconds) was 4.47±0.50 at 20 mmHg, 4.98±0.55 at 50 mmHg and 5.47±0.20 at 80 mmHg. The mean ±SD injection speed (millimeters per seconds) was 1.36±0.15 at 20 mmHg, 1.22±0.14 at 50 mmHg and 1.10±0.04 at 80 mmHg. There was a significant (p<0.05) difference between the 20 and 80 mmHg groups in mean injection duration and injection speed.<h4>Conclusion</h4>The CO2 gas driven injector allows a safe IOL injection even at elevated IOP. Although the implantation time is slightly extended at higher IOPs, this does not seem to be clinically relevant. No IOL damage was observed at these pressure settings.Jan N WeindlerTadas NaujokaitisSonja K SchickhardtRamin KhoramniaGerd U AuffarthPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 7, p e0254901 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Jan N Weindler
Tadas Naujokaitis
Sonja K Schickhardt
Ramin Khoramnia
Gerd U Auffarth
Injection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.
description <h4>Purpose</h4>Experimental study to measure the intraocular lens (IOL) injection time and injection speed at different intraocular pressure (IOP) settings when using the AutonoMe® injector.<h4>Methods</h4>In this experimental study, following phacoemulsification in porcine cadaver eyes, a trocar was inserted at pars plana with a connected infusion and IOPs of 20, 50 and 80 mmHg were generated by altering the infusion height. Twelve CO2 gas-driven injectors were used to implant an IOL via a corneal incision of 2.2 mm. For each IOP setting, the duration of the IOL injection and the injection speed was measured by analyzing a video recording of the procedure.<h4>Results</h4>The mean ±SD injection time (seconds) was 4.47±0.50 at 20 mmHg, 4.98±0.55 at 50 mmHg and 5.47±0.20 at 80 mmHg. The mean ±SD injection speed (millimeters per seconds) was 1.36±0.15 at 20 mmHg, 1.22±0.14 at 50 mmHg and 1.10±0.04 at 80 mmHg. There was a significant (p<0.05) difference between the 20 and 80 mmHg groups in mean injection duration and injection speed.<h4>Conclusion</h4>The CO2 gas driven injector allows a safe IOL injection even at elevated IOP. Although the implantation time is slightly extended at higher IOPs, this does not seem to be clinically relevant. No IOL damage was observed at these pressure settings.
format article
author Jan N Weindler
Tadas Naujokaitis
Sonja K Schickhardt
Ramin Khoramnia
Gerd U Auffarth
author_facet Jan N Weindler
Tadas Naujokaitis
Sonja K Schickhardt
Ramin Khoramnia
Gerd U Auffarth
author_sort Jan N Weindler
title Injection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.
title_short Injection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.
title_full Injection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.
title_fullStr Injection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.
title_full_unstemmed Injection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.
title_sort injection time related to intraocular pressure using a co2 driven preloaded injector: an experimental laboratory study.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/7f3d1ca565da40aa91059e8c07323a1e
work_keys_str_mv AT jannweindler injectiontimerelatedtointraocularpressureusingaco2drivenpreloadedinjectoranexperimentallaboratorystudy
AT tadasnaujokaitis injectiontimerelatedtointraocularpressureusingaco2drivenpreloadedinjectoranexperimentallaboratorystudy
AT sonjakschickhardt injectiontimerelatedtointraocularpressureusingaco2drivenpreloadedinjectoranexperimentallaboratorystudy
AT raminkhoramnia injectiontimerelatedtointraocularpressureusingaco2drivenpreloadedinjectoranexperimentallaboratorystudy
AT gerduauffarth injectiontimerelatedtointraocularpressureusingaco2drivenpreloadedinjectoranexperimentallaboratorystudy
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