Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory

Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory

How emotions affect memory is an open question. Here the authors establish learnt hopeful and learnt helpless mouse models, and find that posterior basolateral amygdala to ventral hippocampal CA1 monosynaptic glutamatergic inputs link emotions to spatial memory performance.

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Detalles Bibliográficos
Autores principales: Ying Yang, Zhi-Hao Wang, Sen Jin, Di Gao, Nan Liu, Shan-Ping Chen, Sinan Zhang, Qing Liu, Enjie Liu, Xin Wang, Xiao Liang, Pengfei Wei, Xiaoguang Li, Yin Li, Chenyu Yue, Hong-lian Li, Ya-Li Wang, Qun Wang, Dan Ke, Qingguo Xie, Fuqiang Xu, Liping Wang, Jian-Zhi Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
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Acceso en línea:https://doaj.org/article/7f41dda76a8c4b2f92e1866dc5234751
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Sumario:How emotions affect memory is an open question. Here the authors establish learnt hopeful and learnt helpless mouse models, and find that posterior basolateral amygdala to ventral hippocampal CA1 monosynaptic glutamatergic inputs link emotions to spatial memory performance.

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