Triggerable tough hydrogels for gastric resident dosage forms

The use of drug delivery systems for the gastrointestinal tract has been faced with a number of drawbacks related to their prolonged use. Here, the authors develop a drug-loaded hydrogel with high strength to withstand long-term gastrointestinal motility and can be triggered to dissolve on demand.

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Detalles Bibliográficos
Autores principales:	Jinyao Liu, Yan Pang, Shiyi Zhang, Cody Cleveland, Xiaolei Yin, Lucas Booth, Jiaqi Lin, Young-Ah Lucy Lee, Hormoz Mazdiyasni, Sarah Saxton, Ameya R. Kirtane, Thomas von Erlach, Jaimie Rogner, Robert Langer, Giovanni Traverso
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7f4463389f3940b0989734721e7106d0
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spelling	oai:doaj.org-article:7f4463389f3940b0989734721e7106d02021-12-02T14:16:55ZTriggerable tough hydrogels for gastric resident dosage forms10.1038/s41467-017-00144-z2041-1723https://doaj.org/article/7f4463389f3940b0989734721e7106d02017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00144-zhttps://doaj.org/toc/2041-1723The use of drug delivery systems for the gastrointestinal tract has been faced with a number of drawbacks related to their prolonged use. Here, the authors develop a drug-loaded hydrogel with high strength to withstand long-term gastrointestinal motility and can be triggered to dissolve on demand.Jinyao LiuYan PangShiyi ZhangCody ClevelandXiaolei YinLucas BoothJiaqi LinYoung-Ah Lucy LeeHormoz MazdiyasniSarah SaxtonAmeya R. KirtaneThomas von ErlachJaimie RognerRobert LangerGiovanni TraversoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jinyao Liu Yan Pang Shiyi Zhang Cody Cleveland Xiaolei Yin Lucas Booth Jiaqi Lin Young-Ah Lucy Lee Hormoz Mazdiyasni Sarah Saxton Ameya R. Kirtane Thomas von Erlach Jaimie Rogner Robert Langer Giovanni Traverso Triggerable tough hydrogels for gastric resident dosage forms
description	The use of drug delivery systems for the gastrointestinal tract has been faced with a number of drawbacks related to their prolonged use. Here, the authors develop a drug-loaded hydrogel with high strength to withstand long-term gastrointestinal motility and can be triggered to dissolve on demand.
format	article
author	Jinyao Liu Yan Pang Shiyi Zhang Cody Cleveland Xiaolei Yin Lucas Booth Jiaqi Lin Young-Ah Lucy Lee Hormoz Mazdiyasni Sarah Saxton Ameya R. Kirtane Thomas von Erlach Jaimie Rogner Robert Langer Giovanni Traverso
author_facet	Jinyao Liu Yan Pang Shiyi Zhang Cody Cleveland Xiaolei Yin Lucas Booth Jiaqi Lin Young-Ah Lucy Lee Hormoz Mazdiyasni Sarah Saxton Ameya R. Kirtane Thomas von Erlach Jaimie Rogner Robert Langer Giovanni Traverso
author_sort	Jinyao Liu
title	Triggerable tough hydrogels for gastric resident dosage forms
title_short	Triggerable tough hydrogels for gastric resident dosage forms
title_full	Triggerable tough hydrogels for gastric resident dosage forms
title_fullStr	Triggerable tough hydrogels for gastric resident dosage forms
title_full_unstemmed	Triggerable tough hydrogels for gastric resident dosage forms
title_sort	triggerable tough hydrogels for gastric resident dosage forms
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7f4463389f3940b0989734721e7106d0
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Triggerable tough hydrogels for gastric resident dosage forms

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