Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects

Shayan Motamedi-Fakhr,1 Rachel C Wilson,1 Richard Iles2 1PneumaCare Ltd, Ely, UK; 2Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Purpose: Differences in tidal breathing patterns have been reported between patients with chronic obstructive pulmonary disease (COPD) and healthy ind...

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Autores principales:	Motamedi-Fakhr S, Wilson RC, Iles R
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Structured light plethysmography tidal breathing chronic obstructive pulmonary disease IE50 thoraco–abdominal asynchrony. Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/7f4b4cfff4764b14adfa099358c724ff
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spelling	oai:doaj.org-article:7f4b4cfff4764b14adfa099358c724ff2021-12-02T10:09:22ZTidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects1179-1470https://doaj.org/article/7f4b4cfff4764b14adfa099358c724ff2016-12-01T00:00:00Zhttps://www.dovepress.com/tidal-breathing-patterns-derived-from-structured-light-plethysmography-peer-reviewed-article-MDERhttps://doaj.org/toc/1179-1470Shayan Motamedi-Fakhr,1 Rachel C Wilson,1 Richard Iles2 1PneumaCare Ltd, Ely, UK; 2Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Purpose: Differences in tidal breathing patterns have been reported between patients with chronic obstructive pulmonary disease (COPD) and healthy individuals using traditional measurement techniques. This feasibility study examined whether structured light plethysmography (SLP) – a noncontact, light-based technique – could also detect differences in tidal breathing patterns between patients with COPD and healthy subjects. Patients and methods: A 5 min period of tidal (quiet) breathing was recorded in each patient with COPD (n=31) and each healthy subject (n=31), matched for age, body mass index, and sex. For every participant, the median and interquartile range (IQR; denoting within-subject variability) of 12 tidal breathing parameters were calculated. Individual data were then combined by cohort and summarized by its median and IQR. Results: After correction for multiple comparisons, inspiratory time (median tI) and its variability (IQR of tI) were lower in patients with COPD (p<0.001 and p<0.01, respectively) as were ratios derived from tI (tI/tE and tI/tTot, both p<0.01) and their variability (p<0.01 and p<0.05, respectively). IE50SLP (the ratio of inspiratory to expiratory flow at 50% tidal volume calculated from the SLP signal) was higher (p<0.001) in COPD while SLP-derived time to reach peak tidal expiratory flow over expiratory time (median tPTEFSLP/tE) was shorter (p<0.01) and considerably less variable (p<0.001). Thoraco–abdominal asynchrony was increased (p<0.05) in COPD. Conclusion: These early observations suggest that, like traditional techniques, SLP is able to detect different breathing patterns in COPD patients compared with subjects with no respiratory disease. This provides support for further investigation into the potential uses of SLP in assessing clinical conditions and interventions. Keywords: structured light plethysmography, tidal breathing, chronic obstructive pulmonary disease, IE50, thoraco–abdominal asynchronyMotamedi-Fakhr SWilson RCIles RDove Medical PressarticleStructured light plethysmographytidal breathingchronic obstructive pulmonary diseaseIE50thoraco–abdominal asynchrony.Medical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol Volume 10, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Structured light plethysmography tidal breathing chronic obstructive pulmonary disease IE50 thoraco–abdominal asynchrony. Medical technology R855-855.5
spellingShingle	Structured light plethysmography tidal breathing chronic obstructive pulmonary disease IE50 thoraco–abdominal asynchrony. Medical technology R855-855.5 Motamedi-Fakhr S Wilson RC Iles R Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects
description	Shayan Motamedi-Fakhr,1 Rachel C Wilson,1 Richard Iles2 1PneumaCare Ltd, Ely, UK; 2Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Purpose: Differences in tidal breathing patterns have been reported between patients with chronic obstructive pulmonary disease (COPD) and healthy individuals using traditional measurement techniques. This feasibility study examined whether structured light plethysmography (SLP) – a noncontact, light-based technique – could also detect differences in tidal breathing patterns between patients with COPD and healthy subjects. Patients and methods: A 5 min period of tidal (quiet) breathing was recorded in each patient with COPD (n=31) and each healthy subject (n=31), matched for age, body mass index, and sex. For every participant, the median and interquartile range (IQR; denoting within-subject variability) of 12 tidal breathing parameters were calculated. Individual data were then combined by cohort and summarized by its median and IQR. Results: After correction for multiple comparisons, inspiratory time (median tI) and its variability (IQR of tI) were lower in patients with COPD (p<0.001 and p<0.01, respectively) as were ratios derived from tI (tI/tE and tI/tTot, both p<0.01) and their variability (p<0.01 and p<0.05, respectively). IE50SLP (the ratio of inspiratory to expiratory flow at 50% tidal volume calculated from the SLP signal) was higher (p<0.001) in COPD while SLP-derived time to reach peak tidal expiratory flow over expiratory time (median tPTEFSLP/tE) was shorter (p<0.01) and considerably less variable (p<0.001). Thoraco–abdominal asynchrony was increased (p<0.05) in COPD. Conclusion: These early observations suggest that, like traditional techniques, SLP is able to detect different breathing patterns in COPD patients compared with subjects with no respiratory disease. This provides support for further investigation into the potential uses of SLP in assessing clinical conditions and interventions. Keywords: structured light plethysmography, tidal breathing, chronic obstructive pulmonary disease, IE50, thoraco–abdominal asynchrony
format	article
author	Motamedi-Fakhr S Wilson RC Iles R
author_facet	Motamedi-Fakhr S Wilson RC Iles R
author_sort	Motamedi-Fakhr S
title	Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects
title_short	Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects
title_full	Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects
title_fullStr	Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects
title_full_unstemmed	Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects
title_sort	tidal breathing patterns derived from structured light plethysmography in copd patients compared with healthy subjects
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/7f4b4cfff4764b14adfa099358c724ff
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Tidal breathing patterns derived from structured light plethysmography in COPD patients compared with healthy subjects

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