Metabolic landscape of the tumor microenvironment at single cell resolution

Each cell type in the tumour microenvironment has unique metabolic demands enabling specific functions. Here the authors use published single-cell RNA-seq data and develop a computational framework to better understand the heterogeneity of tumour metabolism, highlighting the discordance between resu...

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Detalles Bibliográficos
Autores principales:	Zhengtao Xiao, Ziwei Dai, Jason W. Locasale
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7f52ab1626274a2580f7e81b6893c4ad
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spelling	oai:doaj.org-article:7f52ab1626274a2580f7e81b6893c4ad2021-12-02T17:02:08ZMetabolic landscape of the tumor microenvironment at single cell resolution10.1038/s41467-019-11738-02041-1723https://doaj.org/article/7f52ab1626274a2580f7e81b6893c4ad2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11738-0https://doaj.org/toc/2041-1723Each cell type in the tumour microenvironment has unique metabolic demands enabling specific functions. Here the authors use published single-cell RNA-seq data and develop a computational framework to better understand the heterogeneity of tumour metabolism, highlighting the discordance between results obtained from single cells and bulk tumours.Zhengtao XiaoZiwei DaiJason W. LocasaleNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhengtao Xiao Ziwei Dai Jason W. Locasale Metabolic landscape of the tumor microenvironment at single cell resolution
description	Each cell type in the tumour microenvironment has unique metabolic demands enabling specific functions. Here the authors use published single-cell RNA-seq data and develop a computational framework to better understand the heterogeneity of tumour metabolism, highlighting the discordance between results obtained from single cells and bulk tumours.
format	article
author	Zhengtao Xiao Ziwei Dai Jason W. Locasale
author_facet	Zhengtao Xiao Ziwei Dai Jason W. Locasale
author_sort	Zhengtao Xiao
title	Metabolic landscape of the tumor microenvironment at single cell resolution
title_short	Metabolic landscape of the tumor microenvironment at single cell resolution
title_full	Metabolic landscape of the tumor microenvironment at single cell resolution
title_fullStr	Metabolic landscape of the tumor microenvironment at single cell resolution
title_full_unstemmed	Metabolic landscape of the tumor microenvironment at single cell resolution
title_sort	metabolic landscape of the tumor microenvironment at single cell resolution
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7f52ab1626274a2580f7e81b6893c4ad
work_keys_str_mv	AT zhengtaoxiao metaboliclandscapeofthetumormicroenvironmentatsinglecellresolution AT ziweidai metaboliclandscapeofthetumormicroenvironmentatsinglecellresolution AT jasonwlocasale metaboliclandscapeofthetumormicroenvironmentatsinglecellresolution
_version_	1718381978537951232

Metabolic landscape of the tumor microenvironment at single cell resolution

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