Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus

Retroviral reverse transcriptase from Moloney Murine Leukemia Virus (MoMLV) requires interaction with peptidyl release factor 1. Here, the authors report the crystal structure of this complex, and provide insights into how MoMLV uses the host translation machinery to synthesize its own proteins.

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Autores principales:	Xuhua Tang, Yiping Zhu, Stacey L. Baker, Matthew W. Bowler, Benjamin Jieming Chen, Chen Chen, J. Robert Hogg, Stephen P. Goff, Haiwei Song
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7f530fbe22d7490e8ba014489e46d784
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spelling	oai:doaj.org-article:7f530fbe22d7490e8ba014489e46d7842021-12-02T15:35:41ZStructural basis of suppression of host translation termination by Moloney Murine Leukemia Virus10.1038/ncomms120702041-1723https://doaj.org/article/7f530fbe22d7490e8ba014489e46d7842016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms12070https://doaj.org/toc/2041-1723Retroviral reverse transcriptase from Moloney Murine Leukemia Virus (MoMLV) requires interaction with peptidyl release factor 1. Here, the authors report the crystal structure of this complex, and provide insights into how MoMLV uses the host translation machinery to synthesize its own proteins.Xuhua TangYiping ZhuStacey L. BakerMatthew W. BowlerBenjamin Jieming ChenChen ChenJ. Robert HoggStephen P. GoffHaiwei SongNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xuhua Tang Yiping Zhu Stacey L. Baker Matthew W. Bowler Benjamin Jieming Chen Chen Chen J. Robert Hogg Stephen P. Goff Haiwei Song Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
description	Retroviral reverse transcriptase from Moloney Murine Leukemia Virus (MoMLV) requires interaction with peptidyl release factor 1. Here, the authors report the crystal structure of this complex, and provide insights into how MoMLV uses the host translation machinery to synthesize its own proteins.
format	article
author	Xuhua Tang Yiping Zhu Stacey L. Baker Matthew W. Bowler Benjamin Jieming Chen Chen Chen J. Robert Hogg Stephen P. Goff Haiwei Song
author_facet	Xuhua Tang Yiping Zhu Stacey L. Baker Matthew W. Bowler Benjamin Jieming Chen Chen Chen J. Robert Hogg Stephen P. Goff Haiwei Song
author_sort	Xuhua Tang
title	Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
title_short	Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
title_full	Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
title_fullStr	Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
title_full_unstemmed	Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
title_sort	structural basis of suppression of host translation termination by moloney murine leukemia virus
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/7f530fbe22d7490e8ba014489e46d784
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Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus

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