Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus

Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus

Retroviral reverse transcriptase from Moloney Murine Leukemia Virus (MoMLV) requires interaction with peptidyl release factor 1. Here, the authors report the crystal structure of this complex, and provide insights into how MoMLV uses the host translation machinery to synthesize its own proteins.

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Autores principales: Xuhua Tang, Yiping Zhu, Stacey L. Baker, Matthew W. Bowler, Benjamin Jieming Chen, Chen Chen, J. Robert Hogg, Stephen P. Goff, Haiwei Song
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/7f530fbe22d7490e8ba014489e46d784
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