Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody.

Human cytomegalovirus (HCMV) infections are life-threating to people with a compromised or immature immune system. Upon adhesion, fusion of the virus envelope with the host cell is initiated. In this step, the viral glycoprotein gB is considered to represent the major fusogen. Here, we present for t...

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Autores principales: Nadja Spindler, Uschi Diestel, Joachim D Stump, Anna-Katharina Wiegers, Thomas H Winkler, Heinrich Sticht, Michael Mach, Yves A Muller
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/7f586ff7030f4ab49d370e09ebe9f81c
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