Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting

Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting

Current methods to measure post-translational modifications of receptor tyrosine kinases provide ensemble results. Here the authors develop a single-molecule blotting (SiMBlot) assay that detects site-specific phosphorylation patterns at the single-molecule level.

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Autores principales: Kyung Lock Kim, Daehyung Kim, Seongsil Lee, Su-Jeong Kim, Jung Eun Noh, Joung-Hun Kim, Young Chan Chae, Jong-Bong Lee, Sung Ho Ryu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/7f6cbcfad873447898917074ff03d6b7
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spelling oai:doaj.org-article:7f6cbcfad873447898917074ff03d6b72021-12-02T17:31:17ZPairwise detection of site-specific receptor phosphorylations using single-molecule blotting10.1038/ncomms111072041-1723https://doaj.org/article/7f6cbcfad873447898917074ff03d6b72016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11107https://doaj.org/toc/2041-1723Current methods to measure post-translational modifications of receptor tyrosine kinases provide ensemble results. Here the authors develop a single-molecule blotting (SiMBlot) assay that detects site-specific phosphorylation patterns at the single-molecule level.Kyung Lock KimDaehyung KimSeongsil LeeSu-Jeong KimJung Eun NohJoung-Hun KimYoung Chan ChaeJong-Bong LeeSung Ho RyuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kyung Lock Kim
Daehyung Kim
Seongsil Lee
Su-Jeong Kim
Jung Eun Noh
Joung-Hun Kim
Young Chan Chae
Jong-Bong Lee
Sung Ho Ryu
Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
description Current methods to measure post-translational modifications of receptor tyrosine kinases provide ensemble results. Here the authors develop a single-molecule blotting (SiMBlot) assay that detects site-specific phosphorylation patterns at the single-molecule level.
format article
author Kyung Lock Kim
Daehyung Kim
Seongsil Lee
Su-Jeong Kim
Jung Eun Noh
Joung-Hun Kim
Young Chan Chae
Jong-Bong Lee
Sung Ho Ryu
author_facet Kyung Lock Kim
Daehyung Kim
Seongsil Lee
Su-Jeong Kim
Jung Eun Noh
Joung-Hun Kim
Young Chan Chae
Jong-Bong Lee
Sung Ho Ryu
author_sort Kyung Lock Kim
title Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
title_short Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
title_full Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
title_fullStr Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
title_full_unstemmed Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
title_sort pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/7f6cbcfad873447898917074ff03d6b7
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