Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes

Eduardo Sepúlveda,1,2 Rui Poínhos,2,3 Miguel Constante,4,5 José Pais-Ribeiro,1,2 Paula Freitas,6–8 Davide Carvalho6–8 1Faculty of Psychology and Educational Sciences, University of Porto, Porto, Portugal; 2Associação de Preve...

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Autores principales:	Sepúlveda E, Poínhos R, Constante M, Pais-Ribeiro J, Freitas P, Carvalho D
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/7f72756752fa40b3b66e1b43cc7792a2
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spelling	oai:doaj.org-article:7f72756752fa40b3b66e1b43cc7792a22021-12-02T02:56:51ZRelationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes1178-7007https://doaj.org/article/7f72756752fa40b3b66e1b43cc7792a22015-10-01T00:00:00Zhttps://www.dovepress.com/relationship-between-chronic-complications-hypertension-and-health-rel-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Eduardo Sepúlveda,1,2 Rui Poínhos,2,3 Miguel Constante,4,5 José Pais-Ribeiro,1,2 Paula Freitas,6–8 Davide Carvalho6–8 1Faculty of Psychology and Educational Sciences, University of Porto, Porto, Portugal; 2Associação de Prevenção e Apoio à Diabetes, Porto, Portugal; 3Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal; 4Institute of Psychiatry, King's College London, London, UK; 5Department of Psychiatry, Hospital Beatriz Ângelo, Loures, Portugal; 6Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal; 7Faculty of Medicine, University of Porto, Porto, Portugal; 8Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal Background: The aim of this study was to assess the relationship between health-related quality of life (HRQoL) and the presence or absence of hypertension and diabetes-related chronic complications in type 2 diabetes, and also the association between HRQoL and the number of chronic complications. Methods: One hundred patients with type 2 diabetes were interviewed. HRQoL was evaluated using the age-adjusted Short-Form 36 dimensions (physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health). Results: The mean age of the study population was 62.7±8.7 years; 54.0% were male, and 51.0% were receiving only oral hypoglycemic agents. Chronic complications were related to worse HRQoL in different dimensions: peripheral neuropathy and cardiovascular disease (all, except bodily pain), retinopathy (physical functioning, general health, vitality, and mental health), peripheral arterial disease (physical functioning, role-physical, and general health), and nephropathy (general health and vitality). Hypertension was related to worse general health and vitality. An increased number of chronic complications was associated with worse HRQoL in all dimensions of Short-Form 36 except for the bodily pain dimension. Conclusion: The presence and increased number of diabetes-related chronic complications, and the presence of hypertension were related to worse age-adjusted HRQoL. Peripheral neuropathy and cardiovascular disease were more strongly related to age-adjusted HRQoL. Keywords: retinopathy, nephropathy, peripheral neuropathy, cardiovascular disease, peripheral arterial diseaseSepúlveda EPoínhos RConstante MPais-Ribeiro JFreitas PCarvalho DDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2015, Iss default, Pp 535-542 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Sepúlveda E Poínhos R Constante M Pais-Ribeiro J Freitas P Carvalho D Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes
description	Eduardo Sepúlveda,1,2 Rui Poínhos,2,3 Miguel Constante,4,5 José Pais-Ribeiro,1,2 Paula Freitas,6–8 Davide Carvalho6–8 1Faculty of Psychology and Educational Sciences, University of Porto, Porto, Portugal; 2Associação de Prevenção e Apoio à Diabetes, Porto, Portugal; 3Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal; 4Institute of Psychiatry, King's College London, London, UK; 5Department of Psychiatry, Hospital Beatriz Ângelo, Loures, Portugal; 6Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal; 7Faculty of Medicine, University of Porto, Porto, Portugal; 8Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal Background: The aim of this study was to assess the relationship between health-related quality of life (HRQoL) and the presence or absence of hypertension and diabetes-related chronic complications in type 2 diabetes, and also the association between HRQoL and the number of chronic complications. Methods: One hundred patients with type 2 diabetes were interviewed. HRQoL was evaluated using the age-adjusted Short-Form 36 dimensions (physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health). Results: The mean age of the study population was 62.7±8.7 years; 54.0% were male, and 51.0% were receiving only oral hypoglycemic agents. Chronic complications were related to worse HRQoL in different dimensions: peripheral neuropathy and cardiovascular disease (all, except bodily pain), retinopathy (physical functioning, general health, vitality, and mental health), peripheral arterial disease (physical functioning, role-physical, and general health), and nephropathy (general health and vitality). Hypertension was related to worse general health and vitality. An increased number of chronic complications was associated with worse HRQoL in all dimensions of Short-Form 36 except for the bodily pain dimension. Conclusion: The presence and increased number of diabetes-related chronic complications, and the presence of hypertension were related to worse age-adjusted HRQoL. Peripheral neuropathy and cardiovascular disease were more strongly related to age-adjusted HRQoL. Keywords: retinopathy, nephropathy, peripheral neuropathy, cardiovascular disease, peripheral arterial disease
format	article
author	Sepúlveda E Poínhos R Constante M Pais-Ribeiro J Freitas P Carvalho D
author_facet	Sepúlveda E Poínhos R Constante M Pais-Ribeiro J Freitas P Carvalho D
author_sort	Sepúlveda E
title	Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes
title_short	Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes
title_full	Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes
title_fullStr	Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes
title_full_unstemmed	Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes
title_sort	relationship between chronic complications, hypertension, and health-related quality of life in portuguese patients with type 2 diabetes
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/7f72756752fa40b3b66e1b43cc7792a2
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Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes

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