Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission

Cellular signalling networks provide information to the cell, but the trade-off between accuracy of information transfer and energetic cost of doing so has not been assessed. Here, the authors investigate a MAPK signalling cascade in budding yeast and find that information is maximised per unit ener...

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Auteurs principaux:	Alexander Anders, Bhaswar Ghosh, Timo Glatter, Victor Sourjik
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/7f787051a74d42e59c4e8edc6107be9e
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spelling	oai:doaj.org-article:7f787051a74d42e59c4e8edc6107be9e2021-12-02T16:08:15ZDesign of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission10.1038/s41467-020-17276-42041-1723https://doaj.org/article/7f787051a74d42e59c4e8edc6107be9e2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17276-4https://doaj.org/toc/2041-1723Cellular signalling networks provide information to the cell, but the trade-off between accuracy of information transfer and energetic cost of doing so has not been assessed. Here, the authors investigate a MAPK signalling cascade in budding yeast and find that information is maximised per unit energetic cost.Alexander AndersBhaswar GhoshTimo GlatterVictor SourjikNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alexander Anders Bhaswar Ghosh Timo Glatter Victor Sourjik Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission
description	Cellular signalling networks provide information to the cell, but the trade-off between accuracy of information transfer and energetic cost of doing so has not been assessed. Here, the authors investigate a MAPK signalling cascade in budding yeast and find that information is maximised per unit energetic cost.
format	article
author	Alexander Anders Bhaswar Ghosh Timo Glatter Victor Sourjik
author_facet	Alexander Anders Bhaswar Ghosh Timo Glatter Victor Sourjik
author_sort	Alexander Anders
title	Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission
title_short	Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission
title_full	Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission
title_fullStr	Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission
title_full_unstemmed	Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission
title_sort	design of a mapk signalling cascade balances energetic cost versus accuracy of information transmission
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7f787051a74d42e59c4e8edc6107be9e
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_version_	1718384539643936768

Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission

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