Network connectivity determines cortical thinning in early Parkinson’s disease progression
In Parkinson’s disease (PD), neurodegeneration spreads from the brainstem to the cerebral cortex. Here, in a longitudinal study of PD patients, the authors found that cortical thinning followed neural connectivity from a “disease reservoir”.
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Nature Portfolio
2018
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oai:doaj.org-article:7f79e731502044bfb4caf958775b16e42021-12-02T16:49:24ZNetwork connectivity determines cortical thinning in early Parkinson’s disease progression10.1038/s41467-017-02416-02041-1723https://doaj.org/article/7f79e731502044bfb4caf958775b16e42018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02416-0https://doaj.org/toc/2041-1723In Parkinson’s disease (PD), neurodegeneration spreads from the brainstem to the cerebral cortex. Here, in a longitudinal study of PD patients, the authors found that cortical thinning followed neural connectivity from a “disease reservoir”.Y. YauY. ZeighamiT. E. BakerK. LarcherU. VainikM. DadarV. S. FonovP. HagmannA. GriffaB. MišićD. L. CollinsA. DagherNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q Y. Yau Y. Zeighami T. E. Baker K. Larcher U. Vainik M. Dadar V. S. Fonov P. Hagmann A. Griffa B. Mišić D. L. Collins A. Dagher Network connectivity determines cortical thinning in early Parkinson’s disease progression |
description |
In Parkinson’s disease (PD), neurodegeneration spreads from the brainstem to the cerebral cortex. Here, in a longitudinal study of PD patients, the authors found that cortical thinning followed neural connectivity from a “disease reservoir”. |
format |
article |
author |
Y. Yau Y. Zeighami T. E. Baker K. Larcher U. Vainik M. Dadar V. S. Fonov P. Hagmann A. Griffa B. Mišić D. L. Collins A. Dagher |
author_facet |
Y. Yau Y. Zeighami T. E. Baker K. Larcher U. Vainik M. Dadar V. S. Fonov P. Hagmann A. Griffa B. Mišić D. L. Collins A. Dagher |
author_sort |
Y. Yau |
title |
Network connectivity determines cortical thinning in early Parkinson’s disease progression |
title_short |
Network connectivity determines cortical thinning in early Parkinson’s disease progression |
title_full |
Network connectivity determines cortical thinning in early Parkinson’s disease progression |
title_fullStr |
Network connectivity determines cortical thinning in early Parkinson’s disease progression |
title_full_unstemmed |
Network connectivity determines cortical thinning in early Parkinson’s disease progression |
title_sort |
network connectivity determines cortical thinning in early parkinson’s disease progression |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/7f79e731502044bfb4caf958775b16e4 |
work_keys_str_mv |
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