Network connectivity determines cortical thinning in early Parkinson’s disease progression

In Parkinson’s disease (PD), neurodegeneration spreads from the brainstem to the cerebral cortex. Here, in a longitudinal study of PD patients, the authors found that cortical thinning followed neural connectivity from a “disease reservoir”.

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Autores principales: Y. Yau, Y. Zeighami, T. E. Baker, K. Larcher, U. Vainik, M. Dadar, V. S. Fonov, P. Hagmann, A. Griffa, B. Mišić, D. L. Collins, A. Dagher
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7f79e731502044bfb4caf958775b16e4
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spelling oai:doaj.org-article:7f79e731502044bfb4caf958775b16e42021-12-02T16:49:24ZNetwork connectivity determines cortical thinning in early Parkinson’s disease progression10.1038/s41467-017-02416-02041-1723https://doaj.org/article/7f79e731502044bfb4caf958775b16e42018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02416-0https://doaj.org/toc/2041-1723In Parkinson’s disease (PD), neurodegeneration spreads from the brainstem to the cerebral cortex. Here, in a longitudinal study of PD patients, the authors found that cortical thinning followed neural connectivity from a “disease reservoir”.Y. YauY. ZeighamiT. E. BakerK. LarcherU. VainikM. DadarV. S. FonovP. HagmannA. GriffaB. MišićD. L. CollinsA. DagherNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Y. Yau
Y. Zeighami
T. E. Baker
K. Larcher
U. Vainik
M. Dadar
V. S. Fonov
P. Hagmann
A. Griffa
B. Mišić
D. L. Collins
A. Dagher
Network connectivity determines cortical thinning in early Parkinson’s disease progression
description In Parkinson’s disease (PD), neurodegeneration spreads from the brainstem to the cerebral cortex. Here, in a longitudinal study of PD patients, the authors found that cortical thinning followed neural connectivity from a “disease reservoir”.
format article
author Y. Yau
Y. Zeighami
T. E. Baker
K. Larcher
U. Vainik
M. Dadar
V. S. Fonov
P. Hagmann
A. Griffa
B. Mišić
D. L. Collins
A. Dagher
author_facet Y. Yau
Y. Zeighami
T. E. Baker
K. Larcher
U. Vainik
M. Dadar
V. S. Fonov
P. Hagmann
A. Griffa
B. Mišić
D. L. Collins
A. Dagher
author_sort Y. Yau
title Network connectivity determines cortical thinning in early Parkinson’s disease progression
title_short Network connectivity determines cortical thinning in early Parkinson’s disease progression
title_full Network connectivity determines cortical thinning in early Parkinson’s disease progression
title_fullStr Network connectivity determines cortical thinning in early Parkinson’s disease progression
title_full_unstemmed Network connectivity determines cortical thinning in early Parkinson’s disease progression
title_sort network connectivity determines cortical thinning in early parkinson’s disease progression
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/7f79e731502044bfb4caf958775b16e4
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AT tebaker networkconnectivitydeterminescorticalthinninginearlyparkinsonsdiseaseprogression
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