Cathepsin W Is Required for Escape of Influenza A Virus from Late Endosomes

ABSTRACT Human cathepsin W (CtsW) is a cysteine protease, which was identified in a genome-wide RNA interference (RNAi) screen to be required for influenza A virus (IAV) replication. In this study, we show that reducing the levels of expression of CtsW reduces viral titers for different subtypes of...

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Autores principales: Thomas O. Edinger, Marie O. Pohl, Emilio Yángüez, Silke Stertz
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/7f7d731e2ec249ff90cbde70d238cb43
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