Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression
A deeper knowledge of the immune cell profile within the brain cancer tumor microenvironment (TM) could identify targets to improve immunotherapy efficacy. Here, in glioblastoma, the authors find haematopoietic stem and progenitor cells in the TM, which are associated with poor prognosis and increas...
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Nature Portfolio
2021
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oai:doaj.org-article:7f808554a9294259b8143c4fd9d3ca8b2021-12-02T18:02:41ZTumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression10.1038/s41467-021-23995-z2041-1723https://doaj.org/article/7f808554a9294259b8143c4fd9d3ca8b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23995-zhttps://doaj.org/toc/2041-1723A deeper knowledge of the immune cell profile within the brain cancer tumor microenvironment (TM) could identify targets to improve immunotherapy efficacy. Here, in glioblastoma, the authors find haematopoietic stem and progenitor cells in the TM, which are associated with poor prognosis and increased immunosuppression.I-Na LuCelia DobersalskeLaurèl RauschenbachSarah Teuber-HanselmannAnita SteinbachVivien UllrichShruthi PrasadTobias BlauSied KebirJens T. SivekeJürgen C. BeckerUlrich SureMartin GlasBjörn SchefflerIgor CimaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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Science Q |
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Science Q I-Na Lu Celia Dobersalske Laurèl Rauschenbach Sarah Teuber-Hanselmann Anita Steinbach Vivien Ullrich Shruthi Prasad Tobias Blau Sied Kebir Jens T. Siveke Jürgen C. Becker Ulrich Sure Martin Glas Björn Scheffler Igor Cima Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression |
description |
A deeper knowledge of the immune cell profile within the brain cancer tumor microenvironment (TM) could identify targets to improve immunotherapy efficacy. Here, in glioblastoma, the authors find haematopoietic stem and progenitor cells in the TM, which are associated with poor prognosis and increased immunosuppression. |
format |
article |
author |
I-Na Lu Celia Dobersalske Laurèl Rauschenbach Sarah Teuber-Hanselmann Anita Steinbach Vivien Ullrich Shruthi Prasad Tobias Blau Sied Kebir Jens T. Siveke Jürgen C. Becker Ulrich Sure Martin Glas Björn Scheffler Igor Cima |
author_facet |
I-Na Lu Celia Dobersalske Laurèl Rauschenbach Sarah Teuber-Hanselmann Anita Steinbach Vivien Ullrich Shruthi Prasad Tobias Blau Sied Kebir Jens T. Siveke Jürgen C. Becker Ulrich Sure Martin Glas Björn Scheffler Igor Cima |
author_sort |
I-Na Lu |
title |
Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression |
title_short |
Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression |
title_full |
Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression |
title_fullStr |
Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression |
title_full_unstemmed |
Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression |
title_sort |
tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/7f808554a9294259b8143c4fd9d3ca8b |
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