Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression

A deeper knowledge of the immune cell profile within the brain cancer tumor microenvironment (TM) could identify targets to improve immunotherapy efficacy. Here, in glioblastoma, the authors find haematopoietic stem and progenitor cells in the TM, which are associated with poor prognosis and increas...

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Autores principales: I-Na Lu, Celia Dobersalske, Laurèl Rauschenbach, Sarah Teuber-Hanselmann, Anita Steinbach, Vivien Ullrich, Shruthi Prasad, Tobias Blau, Sied Kebir, Jens T. Siveke, Jürgen C. Becker, Ulrich Sure, Martin Glas, Björn Scheffler, Igor Cima
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7f808554a9294259b8143c4fd9d3ca8b
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spelling oai:doaj.org-article:7f808554a9294259b8143c4fd9d3ca8b2021-12-02T18:02:41ZTumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression10.1038/s41467-021-23995-z2041-1723https://doaj.org/article/7f808554a9294259b8143c4fd9d3ca8b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23995-zhttps://doaj.org/toc/2041-1723A deeper knowledge of the immune cell profile within the brain cancer tumor microenvironment (TM) could identify targets to improve immunotherapy efficacy. Here, in glioblastoma, the authors find haematopoietic stem and progenitor cells in the TM, which are associated with poor prognosis and increased immunosuppression.I-Na LuCelia DobersalskeLaurèl RauschenbachSarah Teuber-HanselmannAnita SteinbachVivien UllrichShruthi PrasadTobias BlauSied KebirJens T. SivekeJürgen C. BeckerUlrich SureMartin GlasBjörn SchefflerIgor CimaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
I-Na Lu
Celia Dobersalske
Laurèl Rauschenbach
Sarah Teuber-Hanselmann
Anita Steinbach
Vivien Ullrich
Shruthi Prasad
Tobias Blau
Sied Kebir
Jens T. Siveke
Jürgen C. Becker
Ulrich Sure
Martin Glas
Björn Scheffler
Igor Cima
Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression
description A deeper knowledge of the immune cell profile within the brain cancer tumor microenvironment (TM) could identify targets to improve immunotherapy efficacy. Here, in glioblastoma, the authors find haematopoietic stem and progenitor cells in the TM, which are associated with poor prognosis and increased immunosuppression.
format article
author I-Na Lu
Celia Dobersalske
Laurèl Rauschenbach
Sarah Teuber-Hanselmann
Anita Steinbach
Vivien Ullrich
Shruthi Prasad
Tobias Blau
Sied Kebir
Jens T. Siveke
Jürgen C. Becker
Ulrich Sure
Martin Glas
Björn Scheffler
Igor Cima
author_facet I-Na Lu
Celia Dobersalske
Laurèl Rauschenbach
Sarah Teuber-Hanselmann
Anita Steinbach
Vivien Ullrich
Shruthi Prasad
Tobias Blau
Sied Kebir
Jens T. Siveke
Jürgen C. Becker
Ulrich Sure
Martin Glas
Björn Scheffler
Igor Cima
author_sort I-Na Lu
title Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression
title_short Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression
title_full Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression
title_fullStr Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression
title_full_unstemmed Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression
title_sort tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7f808554a9294259b8143c4fd9d3ca8b
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