Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation

Ian F Burgess1, Katrina Kay1,2, Nazma A Burgess1, Elizabeth R Brunton11Medical Entomology Centre, Insect Research and Development Limited, Cambridge, 2Leeds Primary Care Trust, Leeds, UKBackground: This was a randomized, assessor-blind, controlled comparison of a soya oil-based medical device shampo...

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Autores principales:	Nazma A Burgess, Katrina Kay, Ian F Burgess, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/7f89e1e338ca403cb2ca9314378d6c2f
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spelling	oai:doaj.org-article:7f89e1e338ca403cb2ca9314378d6c2f2021-12-02T06:59:20ZSoya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation1179-1470https://doaj.org/article/7f89e1e338ca403cb2ca9314378d6c2f2011-03-01T00:00:00Zhttp://www.dovepress.com/soya-oil-based-shampoo-superior-to-05-permethrin-lotion-for-head-louse-a6653https://doaj.org/toc/1179-1470Ian F Burgess1, Katrina Kay1,2, Nazma A Burgess1, Elizabeth R Brunton11Medical Entomology Centre, Insect Research and Development Limited, Cambridge, 2Leeds Primary Care Trust, Leeds, UKBackground: This was a randomized, assessor-blind, controlled comparison of a soya oil-based medical device shampoo with a medicinal permethrin lotion in an alcohol vehicle for treatment of head louse infestation to generate data suitable for a regulatory submission to achieve reimbursable status for the shampoo product.Methods: We treated 91 children and adults, divided between two sites, on two occasions 9 days apart. Participants washed their hair and towel-dried it before treatment. The shampoo was used twice for 30 minutes each time. The lotion was used for 30 minutes followed by rinsing. Assessments were made by dry detection combing on days 2, 9, 11, and 14 after the first treatment. According to present knowledge, this combing technique does not influence the overall head louse populations or outcome of treatment.Results: The soya oil shampoo was significantly (P &lt; 0.01) more effective than the lotion for both intention to treat (62.2% versus 34.8% successful treatment) and per-protocol (74.3% versus 36.8% success) groups. Post-treatment assessments showed the necessity for repeat treatment, but that a 9-day interval was too long because if eggs hatched after the first treatment, the lice could grow old enough to lay eggs before the second treatment.Conclusion: The soya oil-based shampoo was more effective than the permethrin lotion, more cosmetically acceptable, and less irritant.Keywords: pediculosis, medical device, medicinal product, insecticide, vegetable oil Nazma A BurgessKatrina KayIan F Burgesset alDove Medical PressarticleMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2011, Iss default, Pp 35-42 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical technology R855-855.5
spellingShingle	Medical technology R855-855.5 Nazma A Burgess Katrina Kay Ian F Burgess et al Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation
description	Ian F Burgess1, Katrina Kay1,2, Nazma A Burgess1, Elizabeth R Brunton11Medical Entomology Centre, Insect Research and Development Limited, Cambridge, 2Leeds Primary Care Trust, Leeds, UKBackground: This was a randomized, assessor-blind, controlled comparison of a soya oil-based medical device shampoo with a medicinal permethrin lotion in an alcohol vehicle for treatment of head louse infestation to generate data suitable for a regulatory submission to achieve reimbursable status for the shampoo product.Methods: We treated 91 children and adults, divided between two sites, on two occasions 9 days apart. Participants washed their hair and towel-dried it before treatment. The shampoo was used twice for 30 minutes each time. The lotion was used for 30 minutes followed by rinsing. Assessments were made by dry detection combing on days 2, 9, 11, and 14 after the first treatment. According to present knowledge, this combing technique does not influence the overall head louse populations or outcome of treatment.Results: The soya oil shampoo was significantly (P &lt; 0.01) more effective than the lotion for both intention to treat (62.2% versus 34.8% successful treatment) and per-protocol (74.3% versus 36.8% success) groups. Post-treatment assessments showed the necessity for repeat treatment, but that a 9-day interval was too long because if eggs hatched after the first treatment, the lice could grow old enough to lay eggs before the second treatment.Conclusion: The soya oil-based shampoo was more effective than the permethrin lotion, more cosmetically acceptable, and less irritant.Keywords: pediculosis, medical device, medicinal product, insecticide, vegetable oil
format	article
author	Nazma A Burgess Katrina Kay Ian F Burgess et al
author_facet	Nazma A Burgess Katrina Kay Ian F Burgess et al
author_sort	Nazma A Burgess
title	Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation
title_short	Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation
title_full	Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation
title_fullStr	Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation
title_full_unstemmed	Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation
title_sort	soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/7f89e1e338ca403cb2ca9314378d6c2f
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Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation

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