Shifting the optimal stiffness for cell migration
Cell migration is sensitive to environmental stiffness, but how cells sense optimal stiffness is not known. Here the authors develop a model that predicts that the optimum can be shifted by altering the number of active molecular motors and clutches, and verify their model in two cell types.
Guardado en:
Autores principales: | Benjamin L. Bangasser, Ghaidan A. Shamsan, Clarence E. Chan, Kwaku N. Opoku, Erkan Tüzel, Benjamin W. Schlichtmann, Jesse A. Kasim, Benjamin J. Fuller, Brannon R. McCullough, Steven S. Rosenfeld, David J. Odde |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7f8be4a890ad4dfa87e307c6843951c7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
High fidelity blood flow in a patient-specific arteriovenous fistula
por: J. W. S. McCullough, et al.
Publicado: (2021) -
Extracellular matrix stiffness and cell contractility control RNA localization to promote cell migration
por: Tianhong Wang, et al.
Publicado: (2017) -
Plant ecological strategies shift across the Cretaceous-Paleogene boundary.
por: Benjamin Blonder, et al.
Publicado: (2014) -
Design principles for shift current photovoltaics
por: Ashley M. Cook, et al.
Publicado: (2017) -
Fascin limits Myosin activity within Drosophila border cells to control substrate stiffness and promote migration
por: Maureen C Lamb, et al.
Publicado: (2021)