Shifting the optimal stiffness for cell migration

Cell migration is sensitive to environmental stiffness, but how cells sense optimal stiffness is not known. Here the authors develop a model that predicts that the optimum can be shifted by altering the number of active molecular motors and clutches, and verify their model in two cell types.

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Detalles Bibliográficos
Autores principales: Benjamin L. Bangasser, Ghaidan A. Shamsan, Clarence E. Chan, Kwaku N. Opoku, Erkan Tüzel, Benjamin W. Schlichtmann, Jesse A. Kasim, Benjamin J. Fuller, Brannon R. McCullough, Steven S. Rosenfeld, David J. Odde
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7f8be4a890ad4dfa87e307c6843951c7
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