Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review

Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review

Abstract Drug-induced liver injury (DILI) causes one in three market withdrawals due to adverse drug reactions, causing preventable human suffering and massive financial loss. We applied evidence-based methods to investigate the role of preclinical studies in predicting human DILI using two anti-dia...

Full description

Saved in:
Bibliographic Details
Main Authors: Hubert Dirven, Gunn E. Vist, Sricharan Bandhakavi, Jyotsna Mehta, Seneca E. Fitch, Pandora Pound, Rebecca Ram, Breanne Kincaid, Cathalijn H. C. Leenaars, Minjun Chen, Robert A. Wright, Katya Tsaioun
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/7f8d336a0d9f49f98f99309991efd57e
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/7f8d336a0d9f49f98f99309991efd57e

Similar Items