Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering

Injuries of the bone/cartilage and central nervous system are still a serious socio-economic problem. They are an effect of diversified, difficult-to-access tissue structures as well as complex regeneration mechanisms. Currently, commercially available materials partially solve this problem, but the...

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Autores principales: Beata Niemczyk-Soczynska, Angelika Zaszczyńska, Konrad Zabielski, Pawel Sajkiewicz
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Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:7f8e4f2859f74c5aa6ef784dde18b3aa2021-11-25T18:14:33ZHydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering10.3390/ma142268991996-1944https://doaj.org/article/7f8e4f2859f74c5aa6ef784dde18b3aa2021-11-01T00:00:00Zhttps://www.mdpi.com/1996-1944/14/22/6899https://doaj.org/toc/1996-1944Injuries of the bone/cartilage and central nervous system are still a serious socio-economic problem. They are an effect of diversified, difficult-to-access tissue structures as well as complex regeneration mechanisms. Currently, commercially available materials partially solve this problem, but they do not fulfill all of the bone/cartilage and neural tissue engineering requirements such as mechanical properties, biochemical cues or adequate biodegradation. There are still many things to do to provide complete restoration of injured tissues. Recent reports in bone/cartilage and neural tissue engineering give high hopes in designing scaffolds for complete tissue regeneration. This review thoroughly discusses the advantages and disadvantages of currently available commercial scaffolds and sheds new light on the designing of novel polymeric scaffolds composed of hydrogels, electrospun nanofibers, or hydrogels loaded with nano-additives.Beata Niemczyk-SoczynskaAngelika ZaszczyńskaKonrad ZabielskiPawel SajkiewiczMDPI AGarticlescaffoldstissue engineeringpolymerselectrospun nanofibershydrogelsnanoparticlesTechnologyTElectrical engineering. Electronics. Nuclear engineeringTK1-9971Engineering (General). Civil engineering (General)TA1-2040MicroscopyQH201-278.5Descriptive and experimental mechanicsQC120-168.85ENMaterials, Vol 14, Iss 6899, p 6899 (2021)
institution DOAJ
collection DOAJ
language EN
topic scaffolds
tissue engineering
polymers
electrospun nanofibers
hydrogels
nanoparticles
Technology
T
Electrical engineering. Electronics. Nuclear engineering
TK1-9971
Engineering (General). Civil engineering (General)
TA1-2040
Microscopy
QH201-278.5
Descriptive and experimental mechanics
QC120-168.85
spellingShingle scaffolds
tissue engineering
polymers
electrospun nanofibers
hydrogels
nanoparticles
Technology
T
Electrical engineering. Electronics. Nuclear engineering
TK1-9971
Engineering (General). Civil engineering (General)
TA1-2040
Microscopy
QH201-278.5
Descriptive and experimental mechanics
QC120-168.85
Beata Niemczyk-Soczynska
Angelika Zaszczyńska
Konrad Zabielski
Pawel Sajkiewicz
Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering
description Injuries of the bone/cartilage and central nervous system are still a serious socio-economic problem. They are an effect of diversified, difficult-to-access tissue structures as well as complex regeneration mechanisms. Currently, commercially available materials partially solve this problem, but they do not fulfill all of the bone/cartilage and neural tissue engineering requirements such as mechanical properties, biochemical cues or adequate biodegradation. There are still many things to do to provide complete restoration of injured tissues. Recent reports in bone/cartilage and neural tissue engineering give high hopes in designing scaffolds for complete tissue regeneration. This review thoroughly discusses the advantages and disadvantages of currently available commercial scaffolds and sheds new light on the designing of novel polymeric scaffolds composed of hydrogels, electrospun nanofibers, or hydrogels loaded with nano-additives.
format article
author Beata Niemczyk-Soczynska
Angelika Zaszczyńska
Konrad Zabielski
Pawel Sajkiewicz
author_facet Beata Niemczyk-Soczynska
Angelika Zaszczyńska
Konrad Zabielski
Pawel Sajkiewicz
author_sort Beata Niemczyk-Soczynska
title Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering
title_short Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering
title_full Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering
title_fullStr Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering
title_full_unstemmed Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering
title_sort hydrogel, electrospun and composite materials for bone/cartilage and neural tissue engineering
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/7f8e4f2859f74c5aa6ef784dde18b3aa
work_keys_str_mv AT beataniemczyksoczynska hydrogelelectrospunandcompositematerialsforbonecartilageandneuraltissueengineering
AT angelikazaszczynska hydrogelelectrospunandcompositematerialsforbonecartilageandneuraltissueengineering
AT konradzabielski hydrogelelectrospunandcompositematerialsforbonecartilageandneuraltissueengineering
AT pawelsajkiewicz hydrogelelectrospunandcompositematerialsforbonecartilageandneuraltissueengineering
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