A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital

Background: Central pontine myelinolysis (CPM)is unique and rare clinical entity. It could be a neurological complication of prolonged hyponatraemia. Many predisposing risk factors (chronic alcoholism, malnutrition, malignancy) may aggravate the development of CPM. CPM usually have a poor or even fa...

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Autores principales: Azhar Al-Shaibany, Shah Shabahat, Moiz Shahid
Formato: article
Lenguaje:EN
Publicado: Al-Azhar University, Faculty of Medicine (Damietta) 2021
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Acceso en línea:https://doaj.org/article/7f9c5e757cb64d9db0b7aad83beaf19d
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spelling oai:doaj.org-article:7f9c5e757cb64d9db0b7aad83beaf19d2021-12-02T17:15:19ZA Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital2636-41742682-378010.21608/ijma.2021.63169.1268https://doaj.org/article/7f9c5e757cb64d9db0b7aad83beaf19d2021-04-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_163660_d3f924bb5b1fed2cf41eec7195081ed6.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Central pontine myelinolysis (CPM)is unique and rare clinical entity. It could be a neurological complication of prolonged hyponatraemia. Many predisposing risk factors (chronic alcoholism, malnutrition, malignancy) may aggravate the development of CPM. CPM usually have a poor or even fatal outcome. However, CPM does not inevitably have a bad prognosis, and could occur with proper restoration of normal serum sodium concentrations.    Case Summary: Here, we presented a case of a 48-year-oldfemale. She used to drink alcohol. She presented to Our Lady’s Hospital/Navan with a history of four days feeling unwell, confused diarrhea, vomiting and by investigations, she had severe hyponatraemia. She was managed optimally in the ICU with close monitoring of her urea and electrolytes. Unfortunately, she got progressive neurological deficits (lower limbs weakness, and slurred speech) irrespective of gentle treatment of hyponatremia in intensive care unit. After Neurological and radiological input from Dublin institute, CPM confirmed under background of alcoholism and malnutrition. Following the diagnosis of CPM, she was discharged home after been rehabilitated with physiotherapy with ongoing recovery.Azhar Al-ShaibanyShah ShabahatMoiz ShahidAl-Azhar University, Faculty of Medicine (Damietta)articlehyponatremiacentral pontine myelinolysisalcoholismmalnutritionMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 2, Pp 1316-1321 (2021)
institution DOAJ
collection DOAJ
language EN
topic hyponatremia
central pontine myelinolysis
alcoholism
malnutrition
Medicine (General)
R5-920
spellingShingle hyponatremia
central pontine myelinolysis
alcoholism
malnutrition
Medicine (General)
R5-920
Azhar Al-Shaibany
Shah Shabahat
Moiz Shahid
A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital
description Background: Central pontine myelinolysis (CPM)is unique and rare clinical entity. It could be a neurological complication of prolonged hyponatraemia. Many predisposing risk factors (chronic alcoholism, malnutrition, malignancy) may aggravate the development of CPM. CPM usually have a poor or even fatal outcome. However, CPM does not inevitably have a bad prognosis, and could occur with proper restoration of normal serum sodium concentrations.    Case Summary: Here, we presented a case of a 48-year-oldfemale. She used to drink alcohol. She presented to Our Lady’s Hospital/Navan with a history of four days feeling unwell, confused diarrhea, vomiting and by investigations, she had severe hyponatraemia. She was managed optimally in the ICU with close monitoring of her urea and electrolytes. Unfortunately, she got progressive neurological deficits (lower limbs weakness, and slurred speech) irrespective of gentle treatment of hyponatremia in intensive care unit. After Neurological and radiological input from Dublin institute, CPM confirmed under background of alcoholism and malnutrition. Following the diagnosis of CPM, she was discharged home after been rehabilitated with physiotherapy with ongoing recovery.
format article
author Azhar Al-Shaibany
Shah Shabahat
Moiz Shahid
author_facet Azhar Al-Shaibany
Shah Shabahat
Moiz Shahid
author_sort Azhar Al-Shaibany
title A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital
title_short A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital
title_full A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital
title_fullStr A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital
title_full_unstemmed A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital
title_sort case of central pontine myelinolysis due to severe acute prolonged hyponatremia in our county hospital
publisher Al-Azhar University, Faculty of Medicine (Damietta)
publishDate 2021
url https://doaj.org/article/7f9c5e757cb64d9db0b7aad83beaf19d
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