A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital
Background: Central pontine myelinolysis (CPM)is unique and rare clinical entity. It could be a neurological complication of prolonged hyponatraemia. Many predisposing risk factors (chronic alcoholism, malnutrition, malignancy) may aggravate the development of CPM. CPM usually have a poor or even fa...
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Al-Azhar University, Faculty of Medicine (Damietta)
2021
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oai:doaj.org-article:7f9c5e757cb64d9db0b7aad83beaf19d2021-12-02T17:15:19ZA Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital2636-41742682-378010.21608/ijma.2021.63169.1268https://doaj.org/article/7f9c5e757cb64d9db0b7aad83beaf19d2021-04-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_163660_d3f924bb5b1fed2cf41eec7195081ed6.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Central pontine myelinolysis (CPM)is unique and rare clinical entity. It could be a neurological complication of prolonged hyponatraemia. Many predisposing risk factors (chronic alcoholism, malnutrition, malignancy) may aggravate the development of CPM. CPM usually have a poor or even fatal outcome. However, CPM does not inevitably have a bad prognosis, and could occur with proper restoration of normal serum sodium concentrations. Case Summary: Here, we presented a case of a 48-year-oldfemale. She used to drink alcohol. She presented to Our Lady’s Hospital/Navan with a history of four days feeling unwell, confused diarrhea, vomiting and by investigations, she had severe hyponatraemia. She was managed optimally in the ICU with close monitoring of her urea and electrolytes. Unfortunately, she got progressive neurological deficits (lower limbs weakness, and slurred speech) irrespective of gentle treatment of hyponatremia in intensive care unit. After Neurological and radiological input from Dublin institute, CPM confirmed under background of alcoholism and malnutrition. Following the diagnosis of CPM, she was discharged home after been rehabilitated with physiotherapy with ongoing recovery.Azhar Al-ShaibanyShah ShabahatMoiz ShahidAl-Azhar University, Faculty of Medicine (Damietta)articlehyponatremiacentral pontine myelinolysisalcoholismmalnutritionMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 2, Pp 1316-1321 (2021) |
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hyponatremia central pontine myelinolysis alcoholism malnutrition Medicine (General) R5-920 |
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hyponatremia central pontine myelinolysis alcoholism malnutrition Medicine (General) R5-920 Azhar Al-Shaibany Shah Shabahat Moiz Shahid A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital |
description |
Background: Central pontine myelinolysis (CPM)is unique and rare clinical entity. It could be a neurological complication of prolonged hyponatraemia. Many predisposing risk factors (chronic alcoholism, malnutrition, malignancy) may aggravate the development of CPM. CPM usually have a poor or even fatal outcome. However, CPM does not inevitably have a bad prognosis, and could occur with proper restoration of normal serum sodium concentrations. Case Summary: Here, we presented a case of a 48-year-oldfemale. She used to drink alcohol. She presented to Our Lady’s Hospital/Navan with a history of four days feeling unwell, confused diarrhea, vomiting and by investigations, she had severe hyponatraemia. She was managed optimally in the ICU with close monitoring of her urea and electrolytes. Unfortunately, she got progressive neurological deficits (lower limbs weakness, and slurred speech) irrespective of gentle treatment of hyponatremia in intensive care unit. After Neurological and radiological input from Dublin institute, CPM confirmed under background of alcoholism and malnutrition. Following the diagnosis of CPM, she was discharged home after been rehabilitated with physiotherapy with ongoing recovery. |
format |
article |
author |
Azhar Al-Shaibany Shah Shabahat Moiz Shahid |
author_facet |
Azhar Al-Shaibany Shah Shabahat Moiz Shahid |
author_sort |
Azhar Al-Shaibany |
title |
A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital |
title_short |
A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital |
title_full |
A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital |
title_fullStr |
A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital |
title_full_unstemmed |
A Case of Central Pontine Myelinolysis due to Severe Acute Prolonged Hyponatremia in Our County Hospital |
title_sort |
case of central pontine myelinolysis due to severe acute prolonged hyponatremia in our county hospital |
publisher |
Al-Azhar University, Faculty of Medicine (Damietta) |
publishDate |
2021 |
url |
https://doaj.org/article/7f9c5e757cb64d9db0b7aad83beaf19d |
work_keys_str_mv |
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