Quantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction

Abstract Non-atherosclerotic abnormalities of vessel calibre, aneurysm and ectasia, are challenging to quantify and are often overlooked in qualitative reporting. Utilising a novel 3-dimensional (3D) quantitative coronary angiography (QCA) application, we have evaluated the characteristics of normal...

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Autores principales:	Yongcheol Kim, Jonathan James Hyett Bray, Benjamin Waterhouse, Alexander Gall, Georgia May Connolly, Eva Sammut, Vito Domenico Bruno, Robert Tulloh, David Adlam, Thomas W. Johnson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7f9d326eab3243008722e1ba76538cc8
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spelling	oai:doaj.org-article:7f9d326eab3243008722e1ba76538cc82021-12-02T14:01:36ZQuantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction10.1038/s41598-020-80928-42045-2322https://doaj.org/article/7f9d326eab3243008722e1ba76538cc82021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80928-4https://doaj.org/toc/2045-2322Abstract Non-atherosclerotic abnormalities of vessel calibre, aneurysm and ectasia, are challenging to quantify and are often overlooked in qualitative reporting. Utilising a novel 3-dimensional (3D) quantitative coronary angiography (QCA) application, we have evaluated the characteristics of normal, diabetic and aneurysmal or ectatic coronary arteries. We selected 131 individuals under 50 years-of-age, who had undergone coronary angiography for suspected myocardial ischaemia between 1st January 2011 and 31st December 2015, at the Bristol Heart Institute, Bristol, UK. This included 42 patients with angiographically normal coronary arteries, 36 diabetic patients with unobstructed coronaries, and 53 patients with abnormal coronary dilatation (aneurysm and ectasia). A total of 1105 coronary segments were analysed using QAngio XA 3D (Research Edition, Medis medical imaging systems, Leiden, The Netherlands). The combined volume of the major coronary arteries was significantly different between each group (1240 ± 476 mm3 diabetic group, 1646 ± 391 mm3 normal group, and 2072 ± 687 mm3 abnormal group). Moreover, the combined coronary artery volumes correlated with patient body surface area (r = 0.483, p < 0.01). Inter-observer variability was assessed and intraclass correlation coefficient of the total coronary artery volume demonstrated a low variability of 3D QCA (r = 0.996, p < 0.001). Dedicated 3D QCA facilitates reproducible coronary artery volume estimation and allows discrimination of normal and diseased vessels.Yongcheol KimJonathan James Hyett BrayBenjamin WaterhouseAlexander GallGeorgia May ConnollyEva SammutVito Domenico BrunoRobert TullohDavid AdlamThomas W. JohnsonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yongcheol Kim Jonathan James Hyett Bray Benjamin Waterhouse Alexander Gall Georgia May Connolly Eva Sammut Vito Domenico Bruno Robert Tulloh David Adlam Thomas W. Johnson Quantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction
description	Abstract Non-atherosclerotic abnormalities of vessel calibre, aneurysm and ectasia, are challenging to quantify and are often overlooked in qualitative reporting. Utilising a novel 3-dimensional (3D) quantitative coronary angiography (QCA) application, we have evaluated the characteristics of normal, diabetic and aneurysmal or ectatic coronary arteries. We selected 131 individuals under 50 years-of-age, who had undergone coronary angiography for suspected myocardial ischaemia between 1st January 2011 and 31st December 2015, at the Bristol Heart Institute, Bristol, UK. This included 42 patients with angiographically normal coronary arteries, 36 diabetic patients with unobstructed coronaries, and 53 patients with abnormal coronary dilatation (aneurysm and ectasia). A total of 1105 coronary segments were analysed using QAngio XA 3D (Research Edition, Medis medical imaging systems, Leiden, The Netherlands). The combined volume of the major coronary arteries was significantly different between each group (1240 ± 476 mm3 diabetic group, 1646 ± 391 mm3 normal group, and 2072 ± 687 mm3 abnormal group). Moreover, the combined coronary artery volumes correlated with patient body surface area (r = 0.483, p < 0.01). Inter-observer variability was assessed and intraclass correlation coefficient of the total coronary artery volume demonstrated a low variability of 3D QCA (r = 0.996, p < 0.001). Dedicated 3D QCA facilitates reproducible coronary artery volume estimation and allows discrimination of normal and diseased vessels.
format	article
author	Yongcheol Kim Jonathan James Hyett Bray Benjamin Waterhouse Alexander Gall Georgia May Connolly Eva Sammut Vito Domenico Bruno Robert Tulloh David Adlam Thomas W. Johnson
author_facet	Yongcheol Kim Jonathan James Hyett Bray Benjamin Waterhouse Alexander Gall Georgia May Connolly Eva Sammut Vito Domenico Bruno Robert Tulloh David Adlam Thomas W. Johnson
author_sort	Yongcheol Kim
title	Quantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction
title_short	Quantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction
title_full	Quantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction
title_fullStr	Quantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction
title_full_unstemmed	Quantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction
title_sort	quantitative evaluation and comparison of coronary artery characteristics by 3d coronary volume reconstruction
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7f9d326eab3243008722e1ba76538cc8
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Quantitative evaluation and comparison of coronary artery characteristics by 3D coronary volume reconstruction

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