Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor

Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor

The Hepatocyte growth factor (HGF) and its receptor (MET) promote several physiological activities such as tissue regeneration and protection from cell injury of epithelial, endothelial, neuronal and muscle cells. The therapeutic potential of MET activation has been scrutinized in the treatment of a...

Full description

Saved in:
Bibliographic Details
Main Authors: Claudia Desole, Simona Gallo, Annapia Vitacolonna, Elisa Vigna, Cristina Basilico, Francesca Montarolo, Francesca Zuppini, Elena Casanova, Riccardo Miggiano, Davide Maria Ferraris, Antonio Bertolotto, Paolo Maria Comoglio, Tiziana Crepaldi
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
HGF
MET
PSI domains
antibody engineering
regenerative medicine
anti-cancer therapy
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/7fa4ce6435b044b2be29090950ec838a
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/7fa4ce6435b044b2be29090950ec838a

Similar Items