Clinical evaluation of silicone gel in the treatment of cleft lip scars

Abstract Upper lip scars are at risk of hypertrophy. Our center therefore uses microporous tape and silicone sheeting for postoperative scar care following cleft lip repair. However, some babies have previously ingested their silicone sheeting, which has the potential for respiratory compromise or g...

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Autores principales:	Chun-Shin Chang, Christopher Glenn Wallace, Yen-Chang Hsiao, Jung-Ju Huang, Zung-Chung Chen, Chee-Jen Chang, Lun-Jou Lo, Philip Kuo-Ting Chen, Jyh-Ping Chen, Yu-Ray Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7fa95e94c5e44725b52aa8e273b847bb
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spelling	oai:doaj.org-article:7fa95e94c5e44725b52aa8e273b847bb2021-12-02T16:07:51ZClinical evaluation of silicone gel in the treatment of cleft lip scars10.1038/s41598-018-25697-x2045-2322https://doaj.org/article/7fa95e94c5e44725b52aa8e273b847bb2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25697-xhttps://doaj.org/toc/2045-2322Abstract Upper lip scars are at risk of hypertrophy. Our center therefore uses microporous tape and silicone sheeting for postoperative scar care following cleft lip repair. However, some babies have previously ingested their silicone sheeting, which has the potential for respiratory compromise or gastrointestinal obstruction. Self-dry silicone gel is reportedly also effective for preventing hypertrophic scars. Hence, we sought to test whether silicone gel, which cannot be ingested whole, might be non-inferior to silicone sheeting for controlling against upper lip scar hypertrophy. This was a mixed prospective and retrospective case-controlled clinical trial involving patients undergoing unilateral cleft lip repair, 29 of whom received standard postoperative silicone sheeting (control group) and another 33 age-matched consecutive patients who received self-dry silicone instead. The Vancouver scar scale, visual analogue scale and photographically assessed scar width assessments were the same in both groups at six months after surgery. In conclusion, silicone gel appears to be non-inferior to silicone sheeting for postoperative care of upper lip scars as judged by scar quality at six months, but silicone sheeting has the safety disadvantage that it can be swallowed whole by babies. It is thus recommended that silicone gel be used for upper lip scar management in babies.Chun-Shin ChangChristopher Glenn WallaceYen-Chang HsiaoJung-Ju HuangZung-Chung ChenChee-Jen ChangLun-Jou LoPhilip Kuo-Ting ChenJyh-Ping ChenYu-Ray ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-5 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chun-Shin Chang Christopher Glenn Wallace Yen-Chang Hsiao Jung-Ju Huang Zung-Chung Chen Chee-Jen Chang Lun-Jou Lo Philip Kuo-Ting Chen Jyh-Ping Chen Yu-Ray Chen Clinical evaluation of silicone gel in the treatment of cleft lip scars
description	Abstract Upper lip scars are at risk of hypertrophy. Our center therefore uses microporous tape and silicone sheeting for postoperative scar care following cleft lip repair. However, some babies have previously ingested their silicone sheeting, which has the potential for respiratory compromise or gastrointestinal obstruction. Self-dry silicone gel is reportedly also effective for preventing hypertrophic scars. Hence, we sought to test whether silicone gel, which cannot be ingested whole, might be non-inferior to silicone sheeting for controlling against upper lip scar hypertrophy. This was a mixed prospective and retrospective case-controlled clinical trial involving patients undergoing unilateral cleft lip repair, 29 of whom received standard postoperative silicone sheeting (control group) and another 33 age-matched consecutive patients who received self-dry silicone instead. The Vancouver scar scale, visual analogue scale and photographically assessed scar width assessments were the same in both groups at six months after surgery. In conclusion, silicone gel appears to be non-inferior to silicone sheeting for postoperative care of upper lip scars as judged by scar quality at six months, but silicone sheeting has the safety disadvantage that it can be swallowed whole by babies. It is thus recommended that silicone gel be used for upper lip scar management in babies.
format	article
author	Chun-Shin Chang Christopher Glenn Wallace Yen-Chang Hsiao Jung-Ju Huang Zung-Chung Chen Chee-Jen Chang Lun-Jou Lo Philip Kuo-Ting Chen Jyh-Ping Chen Yu-Ray Chen
author_facet	Chun-Shin Chang Christopher Glenn Wallace Yen-Chang Hsiao Jung-Ju Huang Zung-Chung Chen Chee-Jen Chang Lun-Jou Lo Philip Kuo-Ting Chen Jyh-Ping Chen Yu-Ray Chen
author_sort	Chun-Shin Chang
title	Clinical evaluation of silicone gel in the treatment of cleft lip scars
title_short	Clinical evaluation of silicone gel in the treatment of cleft lip scars
title_full	Clinical evaluation of silicone gel in the treatment of cleft lip scars
title_fullStr	Clinical evaluation of silicone gel in the treatment of cleft lip scars
title_full_unstemmed	Clinical evaluation of silicone gel in the treatment of cleft lip scars
title_sort	clinical evaluation of silicone gel in the treatment of cleft lip scars
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7fa95e94c5e44725b52aa8e273b847bb
work_keys_str_mv	AT chunshinchang clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT christopherglennwallace clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT yenchanghsiao clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT jungjuhuang clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT zungchungchen clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT cheejenchang clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT lunjoulo clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT philipkuotingchen clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT jyhpingchen clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars AT yuraychen clinicalevaluationofsiliconegelinthetreatmentofcleftlipscars
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Clinical evaluation of silicone gel in the treatment of cleft lip scars

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