TGFβ signaling curbs cell fusion and muscle regeneration

The fusion of muscle progenitor cells to form syncytial myofibers is required for skeletal muscle development and regeneration. Here, the authors describe a novel and specific molecular regulation of muscle cell fusion driven by transforming growth factor beta (TGFβ) signaling.

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Autores principales: Francesco Girardi, Anissa Taleb, Majid Ebrahimi, Asiman Datye, Dilani G. Gamage, Cécile Peccate, Lorenzo Giordani, Douglas P. Millay, Penney M. Gilbert, Bruno Cadot, Fabien Le Grand
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7fadbaa35ce8442d9d056195a3a35cf8
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