Circadian clock mechanism driving mammalian photoperiodism

“Life in a seasonal environment requires appropriate timing of physiological changes to survive, but how the circadian clockwork times these changes remains unclear. Here the authors show that the circadian clock genes BMAL2 and DEC1, in concert with epigenetic pathways in the pituitary, have a cent...

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Autores principales: S. H. Wood, M. M. Hindle, Y. Mizoro, Y. Cheng, B. R. C. Saer, K. Miedzinska, H. C. Christian, N. Begley, J. McNeilly, A. S. McNeilly, S. L. Meddle, D. W. Burt, A. S. I. Loudon
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/7fb5add7468b4e49b866c4366595cefd
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spelling oai:doaj.org-article:7fb5add7468b4e49b866c4366595cefd2021-12-02T19:02:36ZCircadian clock mechanism driving mammalian photoperiodism10.1038/s41467-020-18061-z2041-1723https://doaj.org/article/7fb5add7468b4e49b866c4366595cefd2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18061-zhttps://doaj.org/toc/2041-1723“Life in a seasonal environment requires appropriate timing of physiological changes to survive, but how the circadian clockwork times these changes remains unclear. Here the authors show that the circadian clock genes BMAL2 and DEC1, in concert with epigenetic pathways in the pituitary, have a central role in seasonal timekeeping in mammals.”S. H. WoodM. M. HindleY. MizoroY. ChengB. R. C. SaerK. MiedzinskaH. C. ChristianN. BegleyJ. McNeillyA. S. McNeillyS. L. MeddleD. W. BurtA. S. I. LoudonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
S. H. Wood
M. M. Hindle
Y. Mizoro
Y. Cheng
B. R. C. Saer
K. Miedzinska
H. C. Christian
N. Begley
J. McNeilly
A. S. McNeilly
S. L. Meddle
D. W. Burt
A. S. I. Loudon
Circadian clock mechanism driving mammalian photoperiodism
description “Life in a seasonal environment requires appropriate timing of physiological changes to survive, but how the circadian clockwork times these changes remains unclear. Here the authors show that the circadian clock genes BMAL2 and DEC1, in concert with epigenetic pathways in the pituitary, have a central role in seasonal timekeeping in mammals.”
format article
author S. H. Wood
M. M. Hindle
Y. Mizoro
Y. Cheng
B. R. C. Saer
K. Miedzinska
H. C. Christian
N. Begley
J. McNeilly
A. S. McNeilly
S. L. Meddle
D. W. Burt
A. S. I. Loudon
author_facet S. H. Wood
M. M. Hindle
Y. Mizoro
Y. Cheng
B. R. C. Saer
K. Miedzinska
H. C. Christian
N. Begley
J. McNeilly
A. S. McNeilly
S. L. Meddle
D. W. Burt
A. S. I. Loudon
author_sort S. H. Wood
title Circadian clock mechanism driving mammalian photoperiodism
title_short Circadian clock mechanism driving mammalian photoperiodism
title_full Circadian clock mechanism driving mammalian photoperiodism
title_fullStr Circadian clock mechanism driving mammalian photoperiodism
title_full_unstemmed Circadian clock mechanism driving mammalian photoperiodism
title_sort circadian clock mechanism driving mammalian photoperiodism
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/7fb5add7468b4e49b866c4366595cefd
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AT mmhindle circadianclockmechanismdrivingmammalianphotoperiodism
AT ymizoro circadianclockmechanismdrivingmammalianphotoperiodism
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AT brcsaer circadianclockmechanismdrivingmammalianphotoperiodism
AT kmiedzinska circadianclockmechanismdrivingmammalianphotoperiodism
AT hcchristian circadianclockmechanismdrivingmammalianphotoperiodism
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AT slmeddle circadianclockmechanismdrivingmammalianphotoperiodism
AT dwburt circadianclockmechanismdrivingmammalianphotoperiodism
AT asiloudon circadianclockmechanismdrivingmammalianphotoperiodism
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