Circadian clock mechanism driving mammalian photoperiodism
“Life in a seasonal environment requires appropriate timing of physiological changes to survive, but how the circadian clockwork times these changes remains unclear. Here the authors show that the circadian clock genes BMAL2 and DEC1, in concert with epigenetic pathways in the pituitary, have a cent...
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Nature Portfolio
2020
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oai:doaj.org-article:7fb5add7468b4e49b866c4366595cefd2021-12-02T19:02:36ZCircadian clock mechanism driving mammalian photoperiodism10.1038/s41467-020-18061-z2041-1723https://doaj.org/article/7fb5add7468b4e49b866c4366595cefd2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18061-zhttps://doaj.org/toc/2041-1723“Life in a seasonal environment requires appropriate timing of physiological changes to survive, but how the circadian clockwork times these changes remains unclear. Here the authors show that the circadian clock genes BMAL2 and DEC1, in concert with epigenetic pathways in the pituitary, have a central role in seasonal timekeeping in mammals.”S. H. WoodM. M. HindleY. MizoroY. ChengB. R. C. SaerK. MiedzinskaH. C. ChristianN. BegleyJ. McNeillyA. S. McNeillyS. L. MeddleD. W. BurtA. S. I. LoudonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q |
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Science Q S. H. Wood M. M. Hindle Y. Mizoro Y. Cheng B. R. C. Saer K. Miedzinska H. C. Christian N. Begley J. McNeilly A. S. McNeilly S. L. Meddle D. W. Burt A. S. I. Loudon Circadian clock mechanism driving mammalian photoperiodism |
description |
“Life in a seasonal environment requires appropriate timing of physiological changes to survive, but how the circadian clockwork times these changes remains unclear. Here the authors show that the circadian clock genes BMAL2 and DEC1, in concert with epigenetic pathways in the pituitary, have a central role in seasonal timekeeping in mammals.” |
format |
article |
author |
S. H. Wood M. M. Hindle Y. Mizoro Y. Cheng B. R. C. Saer K. Miedzinska H. C. Christian N. Begley J. McNeilly A. S. McNeilly S. L. Meddle D. W. Burt A. S. I. Loudon |
author_facet |
S. H. Wood M. M. Hindle Y. Mizoro Y. Cheng B. R. C. Saer K. Miedzinska H. C. Christian N. Begley J. McNeilly A. S. McNeilly S. L. Meddle D. W. Burt A. S. I. Loudon |
author_sort |
S. H. Wood |
title |
Circadian clock mechanism driving mammalian photoperiodism |
title_short |
Circadian clock mechanism driving mammalian photoperiodism |
title_full |
Circadian clock mechanism driving mammalian photoperiodism |
title_fullStr |
Circadian clock mechanism driving mammalian photoperiodism |
title_full_unstemmed |
Circadian clock mechanism driving mammalian photoperiodism |
title_sort |
circadian clock mechanism driving mammalian photoperiodism |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/7fb5add7468b4e49b866c4366595cefd |
work_keys_str_mv |
AT shwood circadianclockmechanismdrivingmammalianphotoperiodism AT mmhindle circadianclockmechanismdrivingmammalianphotoperiodism AT ymizoro circadianclockmechanismdrivingmammalianphotoperiodism AT ycheng circadianclockmechanismdrivingmammalianphotoperiodism AT brcsaer circadianclockmechanismdrivingmammalianphotoperiodism AT kmiedzinska circadianclockmechanismdrivingmammalianphotoperiodism AT hcchristian circadianclockmechanismdrivingmammalianphotoperiodism AT nbegley circadianclockmechanismdrivingmammalianphotoperiodism AT jmcneilly circadianclockmechanismdrivingmammalianphotoperiodism AT asmcneilly circadianclockmechanismdrivingmammalianphotoperiodism AT slmeddle circadianclockmechanismdrivingmammalianphotoperiodism AT dwburt circadianclockmechanismdrivingmammalianphotoperiodism AT asiloudon circadianclockmechanismdrivingmammalianphotoperiodism |
_version_ |
1718377218758934528 |