CpG Frequency in the 5′ Third of the <italic toggle="yes">env</italic> Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein
ABSTRACT CpG dinucleotide suppression has been reported to allow HIV-1 to evade inhibition by the zinc-finger antiviral protein (ZAP). Here, we show that primate lentiviruses display marked differences in CpG frequencies across their genome, ranging from 0.44% in simian immunodeficiency virus SIVwrc...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/7fb955a32f4b4d7485d84d077ece1b08 |
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