The SUN1-SPDYA interaction plays an essential role in meiosis prophase I

Telomeres attach to the nuclear envelope to facilitate homolog pairing during meiosis prophase I. Here, the authors show that SUN1 and SPDYA interact, and demonstrate that this interaction is important for telomere structure and function, and essential to mice gametogenesis.

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Autores principales: Yanyan Chen, Yan Wang, Juan Chen, Wu Zuo, Yong Fan, Sijia Huang, Yongmei Liu, Guangming Chen, Qing Li, Jinsong Li, Jian Wu, Qian Bian, Chenhui Huang, Ming Lei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7fbbc5f66def47a687968563e913e76a
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spelling oai:doaj.org-article:7fbbc5f66def47a687968563e913e76a2021-12-02T15:49:30ZThe SUN1-SPDYA interaction plays an essential role in meiosis prophase I10.1038/s41467-021-23550-w2041-1723https://doaj.org/article/7fbbc5f66def47a687968563e913e76a2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23550-whttps://doaj.org/toc/2041-1723Telomeres attach to the nuclear envelope to facilitate homolog pairing during meiosis prophase I. Here, the authors show that SUN1 and SPDYA interact, and demonstrate that this interaction is important for telomere structure and function, and essential to mice gametogenesis.Yanyan ChenYan WangJuan ChenWu ZuoYong FanSijia HuangYongmei LiuGuangming ChenQing LiJinsong LiJian WuQian BianChenhui HuangMing LeiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yanyan Chen
Yan Wang
Juan Chen
Wu Zuo
Yong Fan
Sijia Huang
Yongmei Liu
Guangming Chen
Qing Li
Jinsong Li
Jian Wu
Qian Bian
Chenhui Huang
Ming Lei
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
description Telomeres attach to the nuclear envelope to facilitate homolog pairing during meiosis prophase I. Here, the authors show that SUN1 and SPDYA interact, and demonstrate that this interaction is important for telomere structure and function, and essential to mice gametogenesis.
format article
author Yanyan Chen
Yan Wang
Juan Chen
Wu Zuo
Yong Fan
Sijia Huang
Yongmei Liu
Guangming Chen
Qing Li
Jinsong Li
Jian Wu
Qian Bian
Chenhui Huang
Ming Lei
author_facet Yanyan Chen
Yan Wang
Juan Chen
Wu Zuo
Yong Fan
Sijia Huang
Yongmei Liu
Guangming Chen
Qing Li
Jinsong Li
Jian Wu
Qian Bian
Chenhui Huang
Ming Lei
author_sort Yanyan Chen
title The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
title_short The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
title_full The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
title_fullStr The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
title_full_unstemmed The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
title_sort sun1-spdya interaction plays an essential role in meiosis prophase i
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7fbbc5f66def47a687968563e913e76a
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