Quantitative Analysis of Cell Aggregation Dynamics Identifies HDAC Inhibitors as Potential Regulators of Cancer Cell Clustering

Characterization of the molecular mechanisms involved in tumor cell clustering could open the way to new therapeutic strategies. Towards this aim, we used an in vitro quantitative procedure to monitor the anchorage-independent cell aggregation kinetics in a panel of 25 cancer cell lines. The analysi...

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Auteurs principaux:	Fabien Gava, Julie Pignolet, Sébastien Déjean, Odile Mondésert, Renaud Morin, Joseph Agossa, Bernard Ducommun, Valérie Lobjois
Format:	article
Langue:	EN
Publié:	MDPI AG 2021
Sujets:	cancer cell clustering anchorage-independent aggregation transcriptional expression Connectivity Map HDAC inhibitors Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Accès en ligne:	https://doaj.org/article/7fbc2370ea7e4d499deca56e9773a8ed
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Quantitative Analysis of Cell Aggregation Dynamics Identifies HDAC Inhibitors as Potential Regulators of Cancer Cell Clustering

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