The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure
Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) shuttles between the nucleus and cytoplasm to regulate gene expression and RNA metabolism and its low complexity (LC) C-terminal domain facilitates liquid–liquid phase separation and amyloid aggregation. Here, the authors present the cryo-EM struc...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/7fbc850f6f3e46a78b4dbc0a94ba0a02 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|