A novel and effective method to generate human porcine-specific regulatory T cells with high expression of IL-10, TGF-β1 and IL-35
Abstract Organ transplantation remains the most effective treatment for patients with late stage organ failure. Transgenic pigs provide an alternative organ donor source to the limited availability of human organs. However, cellular rejection still remains to be the obstacle for xenotransplantation....
Guardado en:
Autores principales: | Mingqian Li, Judith Eckl, Christiane Geiger, Dolores J. Schendel, Heike Pohla |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7fbf1c589ce943f3a4e6124b4af9f078 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease
por: Ivy M. Dambuza, et al.
Publicado: (2017) -
Parasite-antigen driven expansion of IL-5(-) and IL-5(+) Th2 human subpopulations in lymphatic filariasis and their differential dependence on IL-10 and TGFβ.
por: Rajamanickam Anuradha, et al.
Publicado: (2014) -
IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation
por: Korneliusz Golebski, et al.
Publicado: (2019) -
IL-4 together with IL-1β induces antitumor Th9 cell differentiation in the absence of TGF-β signaling
por: Gang Xue, et al.
Publicado: (2019) -
High number of CD14+B7H4+ monocytes is significantly associated with increased concentrations of IL-4, IL-13, IL-10, and TGF-β1 in tumor microcirculation of lung carcinoma
por: Vuković Jelena, et al.
Publicado: (2021)