A novel and effective method to generate human porcine-specific regulatory T cells with high expression of IL-10, TGF-β1 and IL-35

Abstract Organ transplantation remains the most effective treatment for patients with late stage organ failure. Transgenic pigs provide an alternative organ donor source to the limited availability of human organs. However, cellular rejection still remains to be the obstacle for xenotransplantation....

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Auteurs principaux: Mingqian Li, Judith Eckl, Christiane Geiger, Dolores J. Schendel, Heike Pohla
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/7fbf1c589ce943f3a4e6124b4af9f078
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