FTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity

Sonchus arvensis, the local name for tempuyung, is acknowledged to have many biological activities, including the antioxidant activity. This study aimed to cluster the leaves extracts based on the extracting solvent and to determine the functional groups significantly contributing to the antioxidant...

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Autores principales:	Mohamad Rafi, Winda Rismayani, Rita Merisa Sugiarti, Utami Dyah Syafitri, Wulan Tri Wahyuni, Eti Rohaeti
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Gadjah Mada 2021
Materias:	antioxidant, chemometrics, ftir spectra, sonchus arvensis, total phenolics Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/7fd77dd89ba64a4cb4f34bcea552363b
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spelling	oai:doaj.org-article:7fd77dd89ba64a4cb4f34bcea552363b2021-11-15T06:08:46ZFTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity2338-94272338-948610.22146/ijp.755https://doaj.org/article/7fd77dd89ba64a4cb4f34bcea552363b2021-05-01T00:00:00Zhttps://jurnal.ugm.ac.id/v3/IJP/article/view/755https://doaj.org/toc/2338-9427https://doaj.org/toc/2338-9486Sonchus arvensis, the local name for tempuyung, is acknowledged to have many biological activities, including the antioxidant activity. This study aimed to cluster the leaves extracts based on the extracting solvent and to determine the functional groups significantly contributing to the antioxidant activity. From the water, 10%, 30%, 50%, 70% ethanol, and absolute ethanol extracts, we analyzed the total phenolics content (Folin-Ciocalteu method), antioxidant activity (DPPH method), and the FTIR spectra. The 70% ethanol extract exhibits the highest total phenolics and the highest antioxidant activity. The extracts were grouped based on the extracting solvent using the principal component analysis (PCA) with 95% total variance from its principal component 1 and 2. The partial least square (PLS) regression was employed for finding a functional group from the antioxidant constituents present in the sample extract. We predicted by PLS regression that the –OH and the C-O groups are attributed to the phenolics that give a significant contribution to the antioxidant activity of the S. arvensis leaves.Mohamad RafiWinda RismayaniRita Merisa SugiartiUtami Dyah SyafitriWulan Tri WahyuniEti RohaetiUniversitas Gadjah Madaarticleantioxidant, chemometrics, ftir spectra, sonchus arvensis, total phenolicsPharmacy and materia medicaRS1-441ENIndonesian Journal of Pharmacy, Pp 132-140 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	antioxidant, chemometrics, ftir spectra, sonchus arvensis, total phenolics Pharmacy and materia medica RS1-441
spellingShingle	antioxidant, chemometrics, ftir spectra, sonchus arvensis, total phenolics Pharmacy and materia medica RS1-441 Mohamad Rafi Winda Rismayani Rita Merisa Sugiarti Utami Dyah Syafitri Wulan Tri Wahyuni Eti Rohaeti FTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity
description	Sonchus arvensis, the local name for tempuyung, is acknowledged to have many biological activities, including the antioxidant activity. This study aimed to cluster the leaves extracts based on the extracting solvent and to determine the functional groups significantly contributing to the antioxidant activity. From the water, 10%, 30%, 50%, 70% ethanol, and absolute ethanol extracts, we analyzed the total phenolics content (Folin-Ciocalteu method), antioxidant activity (DPPH method), and the FTIR spectra. The 70% ethanol extract exhibits the highest total phenolics and the highest antioxidant activity. The extracts were grouped based on the extracting solvent using the principal component analysis (PCA) with 95% total variance from its principal component 1 and 2. The partial least square (PLS) regression was employed for finding a functional group from the antioxidant constituents present in the sample extract. We predicted by PLS regression that the –OH and the C-O groups are attributed to the phenolics that give a significant contribution to the antioxidant activity of the S. arvensis leaves.
format	article
author	Mohamad Rafi Winda Rismayani Rita Merisa Sugiarti Utami Dyah Syafitri Wulan Tri Wahyuni Eti Rohaeti
author_facet	Mohamad Rafi Winda Rismayani Rita Merisa Sugiarti Utami Dyah Syafitri Wulan Tri Wahyuni Eti Rohaeti
author_sort	Mohamad Rafi
title	FTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity
title_short	FTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity
title_full	FTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity
title_fullStr	FTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity
title_full_unstemmed	FTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity
title_sort	ftir-based fingerprinting combined with chemometrics for discrimination of sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity
publisher	Universitas Gadjah Mada
publishDate	2021
url	https://doaj.org/article/7fd77dd89ba64a4cb4f34bcea552363b
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FTIR-based fingerprinting combined with chemometrics for discrimination of Sonchus arvensis leaves extracts of various extracting solvents and the correlation with its antioxidant activity

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