PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells

The authors introduce PharmacoSTORM single-molecule imaging that uses fluorescent ligands and immunolabeling for cellular and subcellular nanoscale molecular pharmacology. They demonstrate its capabilities by visualizing cariprazine binding to D3 dopamine receptors on Islands of Calleja granule cell...

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Autores principales: Susanne Prokop, Péter Ábrányi-Balogh, Benjámin Barti, Márton Vámosi, Miklós Zöldi, László Barna, Gabriella M. Urbán, András Dávid Tóth, Barna Dudok, Attila Egyed, Hui Deng, Gian Marco Leggio, László Hunyady, Mario van der Stelt, György M. Keserű, István Katona
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7fdcba0c8de84fc9bca36e38db68d9ba
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spelling oai:doaj.org-article:7fdcba0c8de84fc9bca36e38db68d9ba2021-11-14T12:34:51ZPharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells10.1038/s41467-021-26757-z2041-1723https://doaj.org/article/7fdcba0c8de84fc9bca36e38db68d9ba2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26757-zhttps://doaj.org/toc/2041-1723The authors introduce PharmacoSTORM single-molecule imaging that uses fluorescent ligands and immunolabeling for cellular and subcellular nanoscale molecular pharmacology. They demonstrate its capabilities by visualizing cariprazine binding to D3 dopamine receptors on Islands of Calleja granule cell axons.Susanne ProkopPéter Ábrányi-BaloghBenjámin BartiMárton VámosiMiklós ZöldiLászló BarnaGabriella M. UrbánAndrás Dávid TóthBarna DudokAttila EgyedHui DengGian Marco LeggioLászló HunyadyMario van der SteltGyörgy M. KeserűIstván KatonaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Susanne Prokop
Péter Ábrányi-Balogh
Benjámin Barti
Márton Vámosi
Miklós Zöldi
László Barna
Gabriella M. Urbán
András Dávid Tóth
Barna Dudok
Attila Egyed
Hui Deng
Gian Marco Leggio
László Hunyady
Mario van der Stelt
György M. Keserű
István Katona
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
description The authors introduce PharmacoSTORM single-molecule imaging that uses fluorescent ligands and immunolabeling for cellular and subcellular nanoscale molecular pharmacology. They demonstrate its capabilities by visualizing cariprazine binding to D3 dopamine receptors on Islands of Calleja granule cell axons.
format article
author Susanne Prokop
Péter Ábrányi-Balogh
Benjámin Barti
Márton Vámosi
Miklós Zöldi
László Barna
Gabriella M. Urbán
András Dávid Tóth
Barna Dudok
Attila Egyed
Hui Deng
Gian Marco Leggio
László Hunyady
Mario van der Stelt
György M. Keserű
István Katona
author_facet Susanne Prokop
Péter Ábrányi-Balogh
Benjámin Barti
Márton Vámosi
Miklós Zöldi
László Barna
Gabriella M. Urbán
András Dávid Tóth
Barna Dudok
Attila Egyed
Hui Deng
Gian Marco Leggio
László Hunyady
Mario van der Stelt
György M. Keserű
István Katona
author_sort Susanne Prokop
title PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
title_short PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
title_full PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
title_fullStr PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
title_full_unstemmed PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
title_sort pharmacostorm nanoscale pharmacology reveals cariprazine binding on islands of calleja granule cells
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7fdcba0c8de84fc9bca36e38db68d9ba
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