Free energies of membrane stalk formation from a lipidomics perspective

Fusion of cellular membranes begins with the formation of a stalk. Here, the authors develop a computationally efficient method for coarse-grained simulations of stalk formation and apply this approach to comprehensively analyse how stalk formation is influenced by the membrane lipid composition.

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Detalles Bibliográficos
Autores principales: Chetan S. Poojari, Katharina C. Scherer, Jochen S. Hub
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7fe956e3d14d44cb821553921bcbe0b9
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Sumario:Fusion of cellular membranes begins with the formation of a stalk. Here, the authors develop a computationally efficient method for coarse-grained simulations of stalk formation and apply this approach to comprehensively analyse how stalk formation is influenced by the membrane lipid composition.