Improvements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study

Introduction: The general objective of this research is to improve the quality of colorectal cancer screening (CRC) by assessing, as an indicator of effectiveness, the ability of colonoscopy to detect more advanced adenomas in the exposed group than in the control group. Material and Methods: The pr...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	A. Álvarez-Delgado, M. L. Pérez García, J. M. García-González, H. Iglesias de Sena, A. J. Chamorro, M. F. Lorenzo Gómez, M. Marcos, J. A. Mirón-Canelo
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	colon cancer population-based screening intervention group with a control group effectiveness quality of the intervention Medicine R
Acceso en línea:	https://doaj.org/article/7fefb94e25bf4003a37ad8ef8145db10
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7fefb94e25bf4003a37ad8ef8145db10
record_format	dspace
spelling	oai:doaj.org-article:7fefb94e25bf4003a37ad8ef8145db102021-11-11T17:41:44ZImprovements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study10.3390/jcm102150722077-0383https://doaj.org/article/7fefb94e25bf4003a37ad8ef8145db102021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5072https://doaj.org/toc/2077-0383Introduction: The general objective of this research is to improve the quality of colorectal cancer screening (CRC) by assessing, as an indicator of effectiveness, the ability of colonoscopy to detect more advanced adenomas in the exposed group than in the control group. Material and Methods: The present work is designed as an open-label randomized study on cancer screening, using two groups based on their exposure to the protocol: an exposed to intervention group (EIG, 167), and a control group (CG, 167), without the intervention of the protocol and by 1:1 matching. Results: In 167 patients in the GEI, 449 polyps are visualized and 274 are adenomas (80.58%), of which 100 (36.49%) are advanced adenomas. In the CG (<i>n</i> = 174), there are 321 polyps and 152 adenomas (82.60%). The variables significantly associated by logistic regression to the detection of adenomas are the male sex with an OR of 2.52. The variable time to withdrawal, ≥9 min, is significant at 99% confidence (<i>p</i> = 0.002/OR 34.67) and the fractional dose is significant at 99% (<i>p</i> = 0.009, OR 7.81). Conclusion: Based on the observations made, our study suggests that the intervention in collaboration between primary care and hospital care is effective from a preventive point of view and achieves the objective of effectiveness and quality of the PCCR.A. Álvarez-DelgadoM. L. Pérez GarcíaJ. M. García-GonzálezH. Iglesias de SenaA. J. ChamorroM. F. Lorenzo GómezM. MarcosJ. A. Mirón-CaneloMDPI AGarticlecolon cancerpopulation-based screeningintervention group with a control groupeffectivenessquality of the interventionMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5072, p 5072 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	colon cancer population-based screening intervention group with a control group effectiveness quality of the intervention Medicine R
spellingShingle	colon cancer population-based screening intervention group with a control group effectiveness quality of the intervention Medicine R A. Álvarez-Delgado M. L. Pérez García J. M. García-González H. Iglesias de Sena A. J. Chamorro M. F. Lorenzo Gómez M. Marcos J. A. Mirón-Canelo Improvements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study
description	Introduction: The general objective of this research is to improve the quality of colorectal cancer screening (CRC) by assessing, as an indicator of effectiveness, the ability of colonoscopy to detect more advanced adenomas in the exposed group than in the control group. Material and Methods: The present work is designed as an open-label randomized study on cancer screening, using two groups based on their exposure to the protocol: an exposed to intervention group (EIG, 167), and a control group (CG, 167), without the intervention of the protocol and by 1:1 matching. Results: In 167 patients in the GEI, 449 polyps are visualized and 274 are adenomas (80.58%), of which 100 (36.49%) are advanced adenomas. In the CG (<i>n</i> = 174), there are 321 polyps and 152 adenomas (82.60%). The variables significantly associated by logistic regression to the detection of adenomas are the male sex with an OR of 2.52. The variable time to withdrawal, ≥9 min, is significant at 99% confidence (<i>p</i> = 0.002/OR 34.67) and the fractional dose is significant at 99% (<i>p</i> = 0.009, OR 7.81). Conclusion: Based on the observations made, our study suggests that the intervention in collaboration between primary care and hospital care is effective from a preventive point of view and achieves the objective of effectiveness and quality of the PCCR.
format	article
author	A. Álvarez-Delgado M. L. Pérez García J. M. García-González H. Iglesias de Sena A. J. Chamorro M. F. Lorenzo Gómez M. Marcos J. A. Mirón-Canelo
author_facet	A. Álvarez-Delgado M. L. Pérez García J. M. García-González H. Iglesias de Sena A. J. Chamorro M. F. Lorenzo Gómez M. Marcos J. A. Mirón-Canelo
author_sort	A. Álvarez-Delgado
title	Improvements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study
title_short	Improvements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study
title_full	Improvements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study
title_fullStr	Improvements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study
title_full_unstemmed	Improvements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study
title_sort	improvements in the effectiveness of early detection in colorectal cancer with open-label randomised study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/7fefb94e25bf4003a37ad8ef8145db10
work_keys_str_mv	AT aalvarezdelgado improvementsintheeffectivenessofearlydetectionincolorectalcancerwithopenlabelrandomisedstudy AT mlperezgarcia improvementsintheeffectivenessofearlydetectionincolorectalcancerwithopenlabelrandomisedstudy AT jmgarciagonzalez improvementsintheeffectivenessofearlydetectionincolorectalcancerwithopenlabelrandomisedstudy AT higlesiasdesena improvementsintheeffectivenessofearlydetectionincolorectalcancerwithopenlabelrandomisedstudy AT ajchamorro improvementsintheeffectivenessofearlydetectionincolorectalcancerwithopenlabelrandomisedstudy AT mflorenzogomez improvementsintheeffectivenessofearlydetectionincolorectalcancerwithopenlabelrandomisedstudy AT mmarcos improvementsintheeffectivenessofearlydetectionincolorectalcancerwithopenlabelrandomisedstudy AT jamironcanelo improvementsintheeffectivenessofearlydetectionincolorectalcancerwithopenlabelrandomisedstudy
_version_	1718432010642391040

Improvements in the Effectiveness of Early Detection in Colorectal Cancer with Open-Label Randomised Study

Ejemplares similares