ArfB can displace mRNA to rescue stalled ribosomes
Alternative rescue factor B (ArfB) is an enzyme that releases peptides from stalled ribosomes to allow ribosome recycling. Here the authors carry-out cryo-EM analyses of 70S ribosomes complexed with ArfB on either a short or longer mRNA to reveal distinct modes of ArfB function.
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Nature Portfolio
2020
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oai:doaj.org-article:7ffabda129144820b3a56d356ee51d8b2021-12-02T16:56:51ZArfB can displace mRNA to rescue stalled ribosomes10.1038/s41467-020-19370-z2041-1723https://doaj.org/article/7ffabda129144820b3a56d356ee51d8b2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19370-zhttps://doaj.org/toc/2041-1723Alternative rescue factor B (ArfB) is an enzyme that releases peptides from stalled ribosomes to allow ribosome recycling. Here the authors carry-out cryo-EM analyses of 70S ribosomes complexed with ArfB on either a short or longer mRNA to reveal distinct modes of ArfB function.Christine E. CarboneGabriel DemoRohini MadireddyEgor SvidritskiyAndrei A. KorostelevNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q Christine E. Carbone Gabriel Demo Rohini Madireddy Egor Svidritskiy Andrei A. Korostelev ArfB can displace mRNA to rescue stalled ribosomes |
description |
Alternative rescue factor B (ArfB) is an enzyme that releases peptides from stalled ribosomes to allow ribosome recycling. Here the authors carry-out cryo-EM analyses of 70S ribosomes complexed with ArfB on either a short or longer mRNA to reveal distinct modes of ArfB function. |
format |
article |
author |
Christine E. Carbone Gabriel Demo Rohini Madireddy Egor Svidritskiy Andrei A. Korostelev |
author_facet |
Christine E. Carbone Gabriel Demo Rohini Madireddy Egor Svidritskiy Andrei A. Korostelev |
author_sort |
Christine E. Carbone |
title |
ArfB can displace mRNA to rescue stalled ribosomes |
title_short |
ArfB can displace mRNA to rescue stalled ribosomes |
title_full |
ArfB can displace mRNA to rescue stalled ribosomes |
title_fullStr |
ArfB can displace mRNA to rescue stalled ribosomes |
title_full_unstemmed |
ArfB can displace mRNA to rescue stalled ribosomes |
title_sort |
arfb can displace mrna to rescue stalled ribosomes |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/7ffabda129144820b3a56d356ee51d8b |
work_keys_str_mv |
AT christineecarbone arfbcandisplacemrnatorescuestalledribosomes AT gabrieldemo arfbcandisplacemrnatorescuestalledribosomes AT rohinimadireddy arfbcandisplacemrnatorescuestalledribosomes AT egorsvidritskiy arfbcandisplacemrnatorescuestalledribosomes AT andreiakorostelev arfbcandisplacemrnatorescuestalledribosomes |
_version_ |
1718382690818850816 |