ArfB can displace mRNA to rescue stalled ribosomes

Alternative rescue factor B (ArfB) is an enzyme that releases peptides from stalled ribosomes to allow ribosome recycling. Here the authors carry-out cryo-EM analyses of 70S ribosomes complexed with ArfB on either a short or longer mRNA to reveal distinct modes of ArfB function.

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Autores principales: Christine E. Carbone, Gabriel Demo, Rohini Madireddy, Egor Svidritskiy, Andrei A. Korostelev
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/7ffabda129144820b3a56d356ee51d8b
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spelling oai:doaj.org-article:7ffabda129144820b3a56d356ee51d8b2021-12-02T16:56:51ZArfB can displace mRNA to rescue stalled ribosomes10.1038/s41467-020-19370-z2041-1723https://doaj.org/article/7ffabda129144820b3a56d356ee51d8b2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19370-zhttps://doaj.org/toc/2041-1723Alternative rescue factor B (ArfB) is an enzyme that releases peptides from stalled ribosomes to allow ribosome recycling. Here the authors carry-out cryo-EM analyses of 70S ribosomes complexed with ArfB on either a short or longer mRNA to reveal distinct modes of ArfB function.Christine E. CarboneGabriel DemoRohini MadireddyEgor SvidritskiyAndrei A. KorostelevNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Christine E. Carbone
Gabriel Demo
Rohini Madireddy
Egor Svidritskiy
Andrei A. Korostelev
ArfB can displace mRNA to rescue stalled ribosomes
description Alternative rescue factor B (ArfB) is an enzyme that releases peptides from stalled ribosomes to allow ribosome recycling. Here the authors carry-out cryo-EM analyses of 70S ribosomes complexed with ArfB on either a short or longer mRNA to reveal distinct modes of ArfB function.
format article
author Christine E. Carbone
Gabriel Demo
Rohini Madireddy
Egor Svidritskiy
Andrei A. Korostelev
author_facet Christine E. Carbone
Gabriel Demo
Rohini Madireddy
Egor Svidritskiy
Andrei A. Korostelev
author_sort Christine E. Carbone
title ArfB can displace mRNA to rescue stalled ribosomes
title_short ArfB can displace mRNA to rescue stalled ribosomes
title_full ArfB can displace mRNA to rescue stalled ribosomes
title_fullStr ArfB can displace mRNA to rescue stalled ribosomes
title_full_unstemmed ArfB can displace mRNA to rescue stalled ribosomes
title_sort arfb can displace mrna to rescue stalled ribosomes
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/7ffabda129144820b3a56d356ee51d8b
work_keys_str_mv AT christineecarbone arfbcandisplacemrnatorescuestalledribosomes
AT gabrieldemo arfbcandisplacemrnatorescuestalledribosomes
AT rohinimadireddy arfbcandisplacemrnatorescuestalledribosomes
AT egorsvidritskiy arfbcandisplacemrnatorescuestalledribosomes
AT andreiakorostelev arfbcandisplacemrnatorescuestalledribosomes
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