ArfB can displace mRNA to rescue stalled ribosomes
Alternative rescue factor B (ArfB) is an enzyme that releases peptides from stalled ribosomes to allow ribosome recycling. Here the authors carry-out cryo-EM analyses of 70S ribosomes complexed with ArfB on either a short or longer mRNA to reveal distinct modes of ArfB function.
Guardado en:
Autores principales: | Christine E. Carbone, Gabriel Demo, Rohini Madireddy, Egor Svidritskiy, Andrei A. Korostelev |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7ffabda129144820b3a56d356ee51d8b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation
por: Gabriel Demo, et al.
Publicado: (2021) -
Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine
por: Cha San Koh, et al.
Publicado: (2017) -
Ubiquitination of stalled ribosome triggers ribosome-associated quality control
por: Yoshitaka Matsuo, et al.
Publicado: (2017) -
A stalled-ribosome rescue factor Pth3 is required for mitochondrial translation against antibiotics in Saccharomyces cerevisiae
por: Soichiro Hoshino, et al.
Publicado: (2021) -
Human NMD ensues independently of stable ribosome stalling
por: Evangelos D. Karousis, et al.
Publicado: (2020)