Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex
Questioning what regulates left-right asymmetry breaking in the mouse node: the authors identify a 200 bp stretch of the Dand5 3’UTR where Bicc1 binds, and Cnot proteins downstream of calcium flow regulate the post-transcriptional regulation of Dand5 by Bicc1.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7ffc6f067d6c41829dd863e590035f76 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:7ffc6f067d6c41829dd863e590035f76 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:7ffc6f067d6c41829dd863e590035f762021-12-02T16:32:13ZFluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex10.1038/s41467-021-24295-22041-1723https://doaj.org/article/7ffc6f067d6c41829dd863e590035f762021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24295-2https://doaj.org/toc/2041-1723Questioning what regulates left-right asymmetry breaking in the mouse node: the authors identify a 200 bp stretch of the Dand5 3’UTR where Bicc1 binds, and Cnot proteins downstream of calcium flow regulate the post-transcriptional regulation of Dand5 by Bicc1.Katsura MinegishiBenjamin RothéKaoru R. KomatsuHiroki OnoYayoi IkawaHiromi NishimuraTakanobu A. KatohEriko KajikawaXiaorei SaiEmi MiyashitaKatsuyoshi TakaokaKana BandoHiroshi KiyonariTadashi YamamotoHirohide SaitoDaniel B. ConstamHiroshi HamadaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Katsura Minegishi Benjamin Rothé Kaoru R. Komatsu Hiroki Ono Yayoi Ikawa Hiromi Nishimura Takanobu A. Katoh Eriko Kajikawa Xiaorei Sai Emi Miyashita Katsuyoshi Takaoka Kana Bando Hiroshi Kiyonari Tadashi Yamamoto Hirohide Saito Daniel B. Constam Hiroshi Hamada Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex |
description |
Questioning what regulates left-right asymmetry breaking in the mouse node: the authors identify a 200 bp stretch of the Dand5 3’UTR where Bicc1 binds, and Cnot proteins downstream of calcium flow regulate the post-transcriptional regulation of Dand5 by Bicc1. |
format |
article |
author |
Katsura Minegishi Benjamin Rothé Kaoru R. Komatsu Hiroki Ono Yayoi Ikawa Hiromi Nishimura Takanobu A. Katoh Eriko Kajikawa Xiaorei Sai Emi Miyashita Katsuyoshi Takaoka Kana Bando Hiroshi Kiyonari Tadashi Yamamoto Hirohide Saito Daniel B. Constam Hiroshi Hamada |
author_facet |
Katsura Minegishi Benjamin Rothé Kaoru R. Komatsu Hiroki Ono Yayoi Ikawa Hiromi Nishimura Takanobu A. Katoh Eriko Kajikawa Xiaorei Sai Emi Miyashita Katsuyoshi Takaoka Kana Bando Hiroshi Kiyonari Tadashi Yamamoto Hirohide Saito Daniel B. Constam Hiroshi Hamada |
author_sort |
Katsura Minegishi |
title |
Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex |
title_short |
Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex |
title_full |
Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex |
title_fullStr |
Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex |
title_full_unstemmed |
Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex |
title_sort |
fluid flow-induced left-right asymmetric decay of dand5 mrna in the mouse embryo requires a bicc1-ccr4 rna degradation complex |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/7ffc6f067d6c41829dd863e590035f76 |
work_keys_str_mv |
AT katsuraminegishi fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT benjaminrothe fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT kaorurkomatsu fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT hirokiono fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT yayoiikawa fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT hirominishimura fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT takanobuakatoh fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT erikokajikawa fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT xiaoreisai fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT emimiyashita fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT katsuyoshitakaoka fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT kanabando fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT hiroshikiyonari fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT tadashiyamamoto fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT hirohidesaito fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT danielbconstam fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex AT hiroshihamada fluidflowinducedleftrightasymmetricdecayofdand5mrnainthemouseembryorequiresabicc1ccr4rnadegradationcomplex |
_version_ |
1718383820227477504 |