Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.

Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.

Activation-induced cytidine deminase (Aid), a unique enzyme that deaminates cytosine in DNA, shuttles between the nucleus and the cytoplasm. A recent study proposed a novel function of Aid in active DNA demethylation via deamination of 5-hydroxymethylcytosine, which is converted from 5-methylcytosin...

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Autores principales: Yuko Arioka, Akira Watanabe, Kuniaki Saito, Yasuhiro Yamada
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/800022fb773949099c6f01821e33d4e8
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