CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS
The article presents the results of examination of 97 adolescent girls (mean age 14,96 ± 0,26 years) with hyperprolactinemia (PRL levels above 700 IU/ml): 30 adolescent girls with pituitary microprolactinoma (mean age 14,7 ± 3.2 years) and 67 adolescent girls with functional hyperprolactinemia (mean...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | article |
| Langue: | RU |
| Publié: |
Scientific Сentre for Family Health and Human Reproduction Problems
2012
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/8003ca5177bd4b2399d9bf5c9b6fb77d |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
| Résumé: | The article presents the results of examination of 97 adolescent girls (mean age 14,96 ± 0,26 years) with hyperprolactinemia (PRL levels above 700 IU/ml): 30 adolescent girls with pituitary microprolactinoma (mean age 14,7 ± 3.2 years) and 67 adolescent girls with functional hyperprolactinemia (mean age 14,6 ± 3,4 years). The control group included 35 healthy adolescent girls (mean age 15,8 ± 0,89 years). Hyperprolactinemia (tumor and non-neoplastic) in puberty leads to disorders of sexual development and ovarian-menstrual cycle, followed by neurological symptoms. Elevated concentrations of testosterone, cortisol, DHEA, 17-OH-progesterone and LH/FSH ratio were shown in adolescents with hyperprolactinemia compared to the control group. Macroprolactinemia was estimated in 16,4—20 % of girls with hyperprolactinemia. |
|---|